Olli Kärkkäinen
Associate Professor
School of Pharmacy, Faculty of Health Sciences
I study the effects of different exposures, e.g. alcohol and drugs, to the metabolic processes in the body using metabolomics methods. My coal is to increase our understanding of disease processes to identify novel biomarkers of exposure and to identify new targets for treatment.
Research groups
Projects
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Publications
98/98 items-
An LC-MS untargeted metabolomic comparison between three blood microsampling devices, whole blood, and plasma
Avella, Dennisse; Turunen, Soile; Avgerinou, Glykeria; Petridou, Anatoli; Mougios, Vassilis; Zarei, Iman; Auriola, Seppo; Hanhineva, Kati; Kärkkäinen, Olli, 2026, Metabolomics, 22, 3, 89. A1 Journal article (refereed), original research -
Comparison of fecal and plasma metabolite correlations following nutrition or exercise interventions
Ahmed, Hany; Kärkkäinen, Olli; Babu, Ambrin Farizah; Meuronen, Topi; Koistinen, Ville; Leclercq, Sophie; Amadieu, Camille; Leyrolle, Quentin; Neyrinck, Audrey; Rodriguez, Julie; Csader, Susanne; Schwab, Ursula; Thissen, Jean-Paul; Starkel, Peter; De Timary, Philippe; Layé, Sophie; Delzenne, Nathalie; Hanhineva, Kati, 2026, Metabolomics, 22, 3, 87. A1 Journal article (refereed), original research -
Levothyroxine Treatment During Pregnancy: A Metabolomics Study
Kärkkäinen, Olli; Sahlman, Heidi; Keski‐Nisula, Leea; Rysä, Jaana, 2026, Basic and clinical pharmacology and toxicology, 139, 1, e70246. A1 Journal article (refereed), original research -
Metabolic changes in human plasma samples among workers exposed to diisocyanate products
Sunnarborg, Katriina; Verdonck, Jelle; Poels, Katrien; Godderis, Lode; Porras, Simo P.; Lehtonen, Marko; Rysä, Jaana; Kärkkäinen, Olli; Santonen, Tiina, 2026, Food and chemical toxicology, 215, 116183. A1 Journal article (refereed), original research -
Metabolic pattern across energy imbalance: An exploratory metabolomics study of female body weight extremes including anorexia nervosa and athletes
Lackner, Sonja; Kärkkäinen, Olli; Morkl, Sabrina; Muller, Wolfram; Furhapter-Rieger, Alfred; Hanhineva, Kati; Holasek, Sandra Johanna, 2026, Experimental physiology, [Epub ahead of print 14 July 2026], 1-23. A1 Journal article (refereed), original research -
Metabolomic insights: LC–MS profiling of human placental tissue from SSRI-treated pregnancies
Itkonen, Anna; Kärkkäinen, Olli; Lehtonen, Marko; Sahlman, Heidi; Keski-Nisula, Leea; Rysä, Jaana, 2026, European journal of medical research, 31, 258. A1 Journal article (refereed), original research -
Predictive value of alcohol use questionnaires for adverse pregnancy outcomes: Evidence from a Finnish birth cohort
Nuttunen, Päivi; Purmonen, Timo; Ålander, Ulpu; Kärkkäinen, Olli; Keski‐Nisula, Leea, 2026, Acta obstetricia et gynecologica scandinavica, 105, 6, 1104-1112. A1 Journal article (refereed), original research -
Alterations in the Plasma Metabolome Associated With Maternal Smoking During the First Trimester and Foetal Growth
Masvosva, Wadzanai; Voutilainen, Taija; Lehtonen, Marko; Haikonen, Retu; Auriola, Seppo; Keski‐Nisula, Leea; Rysä, Jaana; Kärkkäinen, Olli, 2025, Basic and clinical pharmacology and toxicology, 136, 5, 1-11. A1 Journal article (refereed), original research -
Bipolar Disorder and Poisoning due to Medicines or Illegal Substances
Niskanen, Mikko; Kärkkäinen, Olli; Taipale, Heidi; Lieslehto, Johannes; Tiihonen, Jari; Hamina, Aleksi, 2025, Acta psychiatrica scandinavica, 152, 4, 299-307. A1 Journal article (refereed), original research -
Blueprint of the distinct metabolite profiles of healthy pig heart chambers
Haikonen, Retu; Meuronen, Topi; Koistinen, Ville; Kärkkäinen, Olli; Tuomainen, Tomi; Solano-Aguilar, Gloria I; Urban, Joseph F; Lehtonen, Marko; Tavi, Pasi; Hanhineva, Kati, 2025, Journal of molecular and cellular cardiology plus, 13, 100462. A1 Journal article (refereed), original research