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Petri Turhanen

Petri Turhanen

Senior Researcher

Faculty of Health Sciences, School of Pharmacy

petri.turhanen@uef.fi | +358 40 355 3857

0403553857
040 3553857
040 355 3857
+358 40 355 3857
+35840 355 3857
040 3553 857
+358 40 3553 857
+35840 3553 857
+358 40 3553857
+35840 3553857
+358403553857

Information Publications

Research groups

Medicinal chemistry and organic synthesis facilit… 01.01.2010 -
Applied chemistry 01.01.2012 -

Publications

67 items

Surface-Modified Silica Hydrogels for the Programmable Release of Bisphosphonate Anti-Osteoporosis Drugs: The Case of Etidronate
Alatzoglou, Fanouria-Eirini G; Vassaki, Maria; Nirgianaki, Kalliopi; Tripodianos, Eleftherios; Turhanen, Petri; Demadis, Konstantinos D; Papathanasiou, Konstantinos E. 2023. Materials. 16:
3-(3-Bromophenyl)-7-acetoxycoumarin
Turhanen, Petri A; Nousiainen, Liisa P; Timonen, Juri M. 2022. Molbank. 2022:
6-Bromo-1-hydroxyhexane-1,1-bisphosphonic Acid Monosodium Salt
Turhanen, Petri A. 2022. Molbank. 2022:
Drug-Inclusive Inorganic–Organic Hybrid Systems for the Controlled Release of the Osteoporosis Drug Zoledronate
Vassaki, Maria; Lazarou, Savvina; Turhanen, Petri; Choquesillo-Lazarte, Duane; Demadis, Konstantinos D. 2022. Molecules. 27:
Editorial: Phosphonate chemistry in drug design and development, Volume II
Turhanen, Petri A; Kafarski, Pawel. 2022. Frontiers in chemistry. 10: . 1054145
Functionalized nanoporous silicon for extraction of Sc from a leach solution
Rahmani, Arezoo; Thapa, Rinez; Aalto, Juha Matti; Turhanen, Petri; Vepsäläinen, Jouko; Lehto, Vesa Pekka; Riikonen, Joakim. 2022. Hydrometallurgy. 211: . 105866
Importance of Organophosphorus Compounds in Medicinal Chemistry Field
Turhanen, Petri A. 2022. Journal of biomedical research & environmental sciences. 3: 195-197
Real-Time On-Site Multielement Analysis of Environmental Waters with a Portable X-ray Fluorescence (pXRF) System
Tiihonen, Tommi E; Nissinen, Tuomo J; Turhanen, Petri A; Vepsäläinen, Jouko J; Riikonen, Joakim; Lehto, Vesa Pekka. 2022. Analytical chemistry. 94: 11739-11744
Synthesis and Theoretical Studies of Aromatic Azaborines
Hirva, Pipsa; Turhanen, Petri; Timonen, Juri M. 2022. Organics. 3: 196-209
Synthesis of the biologically important dideuterium-labelled adenosine triphosphate analogue ApppI(d2)
Turhanen, Petri A. 2022. Beilstein journal of organic chemistry. 18: 1466-1470
Calcium and Strontium Coordination Polymers as Controlled Delivery Systems of the Anti-Osteoporosis Drug Risedronate and the Augmenting Effect of Solubilizers
Vassaki, Maria; Kotoula, Christina; Turhanen, Petri; Choquesillo-Lazarte, Duane; Demadis, Konstantinos D.. 2021. Applied sciences. 11: 11383
Editorial: Phosphonate Chemistry in Drug Design and Development
Turhanen, Petri A; Demadis, Konstantinos D; Kafarski, Pawel. 2021. Frontiers in chemistry. 9: 695128
Meyer-Schuster Rearrangement - Convenient Synthesis of α,ß-Unsaturated α-Iodinated Aldehydes and Ketones
Timonen, Juri M; Turhanen, Petri A. 2021. General chemistry. 7: 200023
Plant-based nanostructured silicon carbide modified with bisphosphonates for metal adsorption
Haluska, Ondrej; Rahmani, Arezoo; Salami, Ayobami; Turhanen, Petri; Vepsäläinen, Jouko; Lappalainen, Reijo; Lehto, Vesa-Pekka; Riikonen, Joakim. 2021. Microporous and mesoporous materials. 324: 111294
Recovery of uranium with bisphosphonate modified mesoporous silicon
Thapa, Rinez; Rahmani, Arezoo; Turhanen, Petri; Taskinen, Antti; Nissinen, Tuomo; Neitola, Raisa; Vepsäläinen, Jouko; Lehto, Vesa-Pekka; Riikonen, Joakim. 2021. Separation and purification technology. 272: 118913
Rapid synthesis of nanostructured porous silicon carbide from biogenic silica
Riikonen, Joakim; Rantanen, Jimi; Thapa, Rinez; Le, Nguyen T; Rigolet, Severinne; Fioux, Philippe; Turhanen, Petri; Bodiford, Nelli K; Kalluri, Jhansi R; lkonen, Timo; Nissinen, Tuomo; Lebeau, Benedicte; Vepsäläinen, Jouko; Coffer, Jeffery L; Lehto, Vesa-Pekka. 2020. Journal of the American Ceramic Society. 2021; 104: 766-775
Self-sacrificial MOFs for ultra-long controlled release of bisphosphonate anti-osteoporotic drugs
Vassaki, Maria; Papathanasiou, Konstantinos; Hadjicharalambous, Chrystalleni; Chandrinou, Daphne; Turhanen, Petri; Choquesillo-Lazarte, Duane; Demadis, Konstantinos. 2020. Chemical communications. 56: 5166-5169
The serendipitous discovery of a new green chemistry method
Turhanen, Petri. 2020. Research Outreach. : 6-9
(E)-Di-iodination of Alkynes Using Dried Dowex H+/NaI Approach
Timonen, Juri M; Turhanen, Petri A. 2019. ACS omega. 4: 14663-14668
Bisphosphonate modified mesoporous silicon for scandium adsorption
Thapa, Rinez; Nissinen, Tuomo; Turhanen, Petri; Määttä, Juha; Vepsäläinen, Jouko; Lehto, Vesa-Pekka; Riikonen, Joakim. 2019. Microporous and mesoporous materials. 2020; 296: 109980
Green and Efficient Esterification Method Using Dried Dowex H+/NaI Approach
Turhanen, Petri; Leppänen, Jukka; Vepsäläinen, Jouko J. 2019. ACS omega. 4: 8974-8984
Bisphosphonate-Generated ATP-Analogs Inhibit Cell Signaling Pathways
Malwal, SR; O'Dowd, B; Feng, X; Turhanen, PA; Shin, CJ; Yao, J; Kim, BK; Baig, N; Zhou, T; Bansal, S; Khade, R;, Zhang, Y; Oldfield, E. 2018. Journal of the American Chemical Society. 140: 7568-7578
Integrated analysis of isopentenyl pyrophosphate (IPP) toxicity in isoprenoid-producing Escherichia coli
George, KW; Thompson, M; Kim, J; Baidoo, EEK; Wang, G; Benites, VT; Petzold, CJ; Chan, LJG; Yilmaz, S; Turhanen, P; Adams, PD; Keasling, JD; Lee, TS. 2018. Metabolic engineering. 47: 60-72
Phosphorus chemistry: from small molecules, to polymers, to pharmaceutical and industrial applications
Papathanasiou, Konstantinos E; Vassaki, Maria; Spinthaki, Argyro; Alatzoglou, Fanouria-Eirini G; Tripodianos, Eleftherios; Turhanen, Petri; Demadis, Konstantinos D. 2018. Pure and applied chemistry. 2019; 91: 421-4411-21
Selective Calcium-Dependent Inhibition of ATP-Gated P2X3 Receptors by Bisphosphonate-Induced Endogenous ATP Analog ApppI
Ishchenko Y, Shakirzyanova A, Giniatullina R, Skorinkin A, Bart G, Turhanen P, Määttä JA, Mönkkönen J, Giniatullin R. 2017. Journal of pharmacology and experimental therapeutics. 361: 472-481
Semi-preparative high-performance countercurrent chromatography method for the purification of chemically synthesized ATP analogue, ApppI.
Puljula E, Turhanen PA. 2017. Journal of chromatography b: analytical technologies in the biomedical and life sciences. 1063: 180-182
Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs
Papathanasiou Konstantinos E, Turhanen Petri, Brueckner Stephan I, Brunner Eike, Demadis Konstantinos D. 2017. Scientific reports. 7: 4743
Synthesis of a Biologically Important Adenosine Triphosphate Analogue, ApppD
Turhanen Petri. 2017. ACS omega. 2: 2835-2838
Preparation of useful building blocks, a-iodo- and bromoalkanols from cyclic ethers using the Dowex H+/NaX (X = I, Br) approach
Turhanen Petri, Vepsäläinen Jouko. 2016. Rsc advances. 6: 15937-15940
Synthesis of medronic acid monoesters and their purification by high-performance countercurrent chromatography or by hydroxyapatite
Puljula Elina, Vepsäläinen Jouko, Turhanen Petri. 2016. Beilstein journal of organic chemistry. 12: 2145-2149
A powerful tool for acid catalyzed organic addition and substitution reactions
Turhanen Petri, Vepsäläinen Jouko. 2015. Rsc advances. 5: 26218-26222
Advanced material and approach for metal ions removal from aqueous solutions
Turhanen Petri A, Vepsäläinen Jouko J, Peräniemi Sirpa. 2015. Scientific reports. 5: 8992
Selective acetylation of primary amino groups with phenyl acetate: simple conversion of polyamines into N,N'-diacetyl derivatives
Ucal Sebahat, Khomutov Alex R, Häkkinen Merja R, Turhanen Petri A, Vepsäläinen Jouko J, Weisell Janne. 2015. Arkivoc. 2015: 42-49
Structural Requirements for Bisphosphonate Binding on Hydroxyapatite: NMR Study of Bisphosphonate Partial Esters
Puljula Elina, Turhanen Petri, Vepsäläinen Jouko, Monteil Maelle, Lecouvey Marc, Weisell Janne. 2015. Acs medicinal chemistry letters. 6: 397-401
Two strategies for the synthesis of the biologically important ATP analogue ApppI, at a multi-milligram scale
Weisell Janne, Vepsäläinen Jouko, Turhanen Petri A. 2015. Beilstein journal of organic chemistry. 11: 2189-2193
Uusi menetelmä ja uusi katalyyttinen järjestelmä selektiivisiin orgaanisiin additio- ja substituutioreaktioihin
Vepsäläinen Jouko, Turhanen Petri. 2015.
Bisphosphonates: How does the structure affect the ability to bind to hydroxyapatite?
Elina Puljula, Aino-Liisa Alanne, Petri Turhanen, Jouko Vepsäläinen, Janne Weisell. 2014.
Synthesis of Triple-Bond-Containing 1-Hydroxy-1,1-bisphosphonic Acid Derivatives To Be Used as Precursors in "Click" Chemistry: Two Examples
Turhanen Petri A. 2014. Journal of organic chemistry. 79: 6330-6335
A bisphosphonate increasing the shoot biomass of the metal hyperaccumulator Noccaea caerulescens
Alanne Aino-Liisa, Peräniemi Sirpa, Turhanen Petri, Tuomainen Marjo, Vepsäläinen Jouko, Tervahauta Arja. 2013. Chemosphere. 2014:95: 566-571
A novel bisphosphonate-based solid phase method for effective removal of chromium(III) from aqueous solutions and tannery effluents
Alanne Aino-Liisa, Tuikka Matti, Tõnsuaadu Kaia, Ylisirniö Markku, Hämäläinen Lea, Turhanen Petri, Vepsäläinen Jouko, Peräniemi Sirpa. 2013. Rsc advances. 3: 14132-14138
An Insoluble Bisphosphonate as a Metal Collector - an Innovative Solution to the Waste Water Problems of the Mining Industry
Aino-Liisa Alanne, Petri Turhanen, Janne Kankkunen, Sirpa Peräniemi, Jouko Vepsäläinen. 2013.
An in vitro method for determining bisphosphonate-binding to hydroxyapatite by 31P NMR
Sankala, E., Alanne, A.-L., Turhanen, P., Weisell, J. and Vepsäläinen.. 2013.
Effect of bisphosphonates on metal accumulation in the metal hyperaccumulator plan Noccaea caerulescens
Alanne A, Tuomainen M, Turhanen P, Peräniemi S, Vepsäläinen J, Kärenlmpi S, Tervahauta A. 2013.
Firefly luciferase inhibitor-conjugated peptide quenches bioluminescence: a versatile tool for real time monitoring cellular uptake of biomolecules
Poutiainen Pekka K, Rönkkö Teemu, Hinkkanen Ari E, Palvimo Jorma J, Närvänen Ale, Turhanen Petri, Laatikainen Reino, Weisell Janne, Pulkkinen Juha T. 2013. Bioconjugate chemistry. 2014:25: 4-10
First bisphosphonate hydrogelators: potential composers of biocompatible gels
Alanne Aino-Liisa, Lahtinen Manu, Löfman Miika, Turhanen Petri, Kolehmainen Erkki, Vepsäläinen Jouko, Sievänen Elina. 2013. Journal of materials chemistry. b. 1: 6201-6212
Method for collecting metals
Turhanen Petri, Peräniemi Sirpa, Vepsäläinen Jouko. 2013.
The selective stepwise chemical hydrolysis of alkylcarbonate groups from novel mixed alkylcarbonate trialkyl ester derivatives of etidronic acid
Turhanen Petri A, Weisell Janne, Vepsäläinen Jouko J. 2013. Rsc advances. 3: 2417-2421
99mTc-labeled partial esters of etidronic acid and their biodistribution in healthy mice
Sankala E, Turhanen P, Weisell J, Monteil M, Lecouvey M, Huhtala T, Närvänen A, Vepsäläinen J. 2012.
Large glucosylthioureidocalixarenes: selective hosts for mono- and bisphosphonates
Torvinen Mika, Kalenius Elina, Sansone Francesco, Casnati Alessandro, Turhanen Petri, Jänis Janne. 2012. Supramolecular chemistry. 24: 228-233
Preparation of mixed trialkyl alkylcarbonate derivates of etidronic acid via an unusual route
Turhanen Petri A, Weisell Janne, Vepsäläinen Jouko J. 2012. Beilstein journal of organic chemistry. 8: 2019-2024
Systematic study of the physicochemical properties of a homologous series of aminobisphosphonates
Alanne Aino-Liisa, Hyvönen Helena, Lahtinen Manu, Ylisirniö Markku, Turhanen Petri, Kolehmainen Erkki, Peräniemi Sirpa, Vepsäläinen Jouko. 2012. Molecules. 17: 10928-10945
A novel strategy for the synthesis of enzymatically stable biotin-DOTA conjugates for in vivo use
Turhanen Petri A, Weisell Janne, Lehtolainen-Dalkilic Pauliina, Määttä Ann-Marie, Vepsäläinen Jouko, Närvänen Ale. 2011. Medchemcomm. 2: 886-888
Alkylaminobisphosphonates: Synthesis, characterization and determination of pKa-values
Saari, A-L.; Ylisirniö, M.; Lahtinen, M.; Hyvönen, H.; Turhanen, P.; Kolehmainen, E.; Peräniemi, S. and Vepsäläinen, J.. 2011.
Alkylaminobisphosphonates: Synthesis, characterization and determination of pKa-values
Saari, A-L.; Ylisirniö, M.; Lahtinen, M.; Hyvönen, H.; Turhanen, P.; Kolehmainen, E.; Peräniemi, S. and Vepsäläinen, J.. 2011.
Synthesis, Characterization and determination of pKa-values of alkylaminobisphosphonates
Saari Aino-Liisa, Ylisirniö, Markku, Lahtinen Manu, Hyvönen Helena, Turhanen Petri, Kolehmainen Erkki, Peräniemi Sirpa, Vepsäläinen Jouko. 2011.
Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions
Turhanen PA, Vepsäläinen JJ. 2008. Beilstein journal of organic chemistry. 4:
A novel strategy for the preparation of naturally occurring phosphocitrate and its partially esterfied derivatives
Turhanen PA, Demadis KD, Peräniemi S, Vepsäläinen JJ. 2007. Journal of organic chemistry. 72: 1468-1471
Synthesis of novel (1-alkanoyloxy-4-alkanoylaminobutylidene)-1,1-bisphosphonic acid derivatives
Turhanen P, Vepsalainen JJ. 2006. Beilstein journal of organic chemistry. 2:2:
Synthesis of novel fatty acid derivatives of etidronic acid
Turhanen PA, Vepsäläinen JJ. 2005. Synthesis: stuttgart. : 3063-3066
The first synthesis of novel (1-alkoxycarbonyloxyethylidene)-1,1-bisphosphonic acid derivatives taking advantage of the rearrangement characteristic of the tetramethyl ester of etidronate
Turhanen PA, Vepsäläinen JJ. 2005. Synthesis: stuttgart. : 2119-2121
One-pot synthesis of 1-[(1-phenyl-1-dialkoxyphosphoryl)-methyl]-2-pyrrolidinone
Turhanen PA, Soininen P, Vepsäläinen JJ. 2004. Letters in organic chemistry. : 343-345
Strategies for the preparation of (1-acetyloxyethylidene)-1,1-bisphosphonic acid derivatives
Turhanen PA, Vepsäläinen JJ. 2004. Synthesis: stuttgart. : 0992-0994
Design and Synthesis of Novel (I-Hydroxyethylidene)-I, I-Bisphosphonic Acid Derivatives as Possible Prodrugs of Etidronate
Turhanen P. 2003. Kuopion yliopiston julkaisuja C. Luonnontieteet ja ympäristötieteet
First synthesis of etidronate partial amides starting from PCI3
Turhanen PA, Niemi R, Peräkylä M, Järvinen T, Vepsäläinen JJ. 2003. Organic and biomolecular chemistry. 1: 3223-3226
Bisphosphonate prodrugs. Synthesis and identification of (1-hydroxyethylidene)-1,1-bisphosphonic acid tetraesters by mass spectrometry, NMR spectroscopy and X-ray crystallography
Turhanen PA, Ahlgren MJ, Järvinen T, Vepsäläinen JJ. 2001. PHOSPHORUS, SULFUR, AND SILICON AND THE RELATED ELEMENTS. 170: 115-133
Bisphosphonate prodrugs: selective synthesis of (1-hydroxyethylidene)-1,1-bisphosphonate partial esters
Turhanen PA, Ahlgren MJ, Järvinen T, Vepsäläinen J. 2001. Synthesis: stuttgart. : 633-637
Bisphosphonate prodrugs: synthesis and vitro evaluation of alkyl and acyloxymethyl esters of etidronic acid as bioreversible prodrugs of etidronate
Niemi R, Turhanen P, Vepsäläinen J, Taipale H, Järvinen T. 2000. European journal of pharmaceutical sciences. 11: 173-180

University of Eastern Finland Joensuu, Kuopio © University of Eastern Finland

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Petri Turhanen

Research groups

Surface-Modified Silica Hydrogels for the Programmable Release of Bisphosphonate Anti-Osteoporosis Drugs: The Case of Etidronate

3-(3-Bromophenyl)-7-acetoxycoumarin

6-Bromo-1-hydroxyhexane-1,1-bisphosphonic Acid Monosodium Salt

Drug-Inclusive Inorganic–Organic Hybrid Systems for the Controlled Release of the Osteoporosis Drug Zoledronate

Editorial: Phosphonate chemistry in drug design and development, Volume II

Functionalized nanoporous silicon for extraction of Sc from a leach solution

Importance of Organophosphorus Compounds in Medicinal Chemistry Field

Real-Time On-Site Multielement Analysis of Environmental Waters with a Portable X-ray Fluorescence (pXRF) System

Synthesis and Theoretical Studies of Aromatic Azaborines

Synthesis of the biologically important dideuterium-labelled adenosine triphosphate analogue ApppI(d2)

Calcium and Strontium Coordination Polymers as Controlled Delivery Systems of the Anti-Osteoporosis Drug Risedronate and the Augmenting Effect of Solubilizers

Editorial: Phosphonate Chemistry in Drug Design and Development

Meyer-Schuster Rearrangement - Convenient Synthesis of α,ß-Unsaturated α-Iodinated Aldehydes and Ketones

Plant-based nanostructured silicon carbide modified with bisphosphonates for metal adsorption

Recovery of uranium with bisphosphonate modified mesoporous silicon

Rapid synthesis of nanostructured porous silicon carbide from biogenic silica

Self-sacrificial MOFs for ultra-long controlled release of bisphosphonate anti-osteoporotic drugs

The serendipitous discovery of a new green chemistry method

(E)-Di-iodination of Alkynes Using Dried Dowex H+/NaI Approach

Bisphosphonate modified mesoporous silicon for scandium adsorption

Green and Efficient Esterification Method Using Dried Dowex H+/NaI Approach

Bisphosphonate-Generated ATP-Analogs Inhibit Cell Signaling Pathways

Integrated analysis of isopentenyl pyrophosphate (IPP) toxicity in isoprenoid-producing Escherichia coli

Phosphorus chemistry: from small molecules, to polymers, to pharmaceutical and industrial applications

Selective Calcium-Dependent Inhibition of ATP-Gated P2X3 Receptors by Bisphosphonate-Induced Endogenous ATP Analog ApppI

Semi-preparative high-performance countercurrent chromatography method for the purification of chemically synthesized ATP analogue, ApppI.

Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs

Synthesis of a Biologically Important Adenosine Triphosphate Analogue, ApppD

Preparation of useful building blocks, a-iodo- and bromoalkanols from cyclic ethers using the Dowex H+/NaX (X = I, Br) approach

Synthesis of medronic acid monoesters and their purification by high-performance countercurrent chromatography or by hydroxyapatite

A powerful tool for acid catalyzed organic addition and substitution reactions

Advanced material and approach for metal ions removal from aqueous solutions

Selective acetylation of primary amino groups with phenyl acetate: simple conversion of polyamines into N,N'-diacetyl derivatives

Structural Requirements for Bisphosphonate Binding on Hydroxyapatite: NMR Study of Bisphosphonate Partial Esters

Two strategies for the synthesis of the biologically important ATP analogue ApppI, at a multi-milligram scale

Uusi menetelmä ja uusi katalyyttinen järjestelmä selektiivisiin orgaanisiin additio- ja substituutioreaktioihin

Bisphosphonates: How does the structure affect the ability to bind to hydroxyapatite?

Synthesis of Triple-Bond-Containing 1-Hydroxy-1,1-bisphosphonic Acid Derivatives To Be Used as Precursors in "Click" Chemistry: Two Examples

A bisphosphonate increasing the shoot biomass of the metal hyperaccumulator Noccaea caerulescens

A novel bisphosphonate-based solid phase method for effective removal of chromium(III) from aqueous solutions and tannery effluents

An Insoluble Bisphosphonate as a Metal Collector - an Innovative Solution to the Waste Water Problems of the Mining Industry

An in vitro method for determining bisphosphonate-binding to hydroxyapatite by 31P NMR

Effect of bisphosphonates on metal accumulation in the metal hyperaccumulator plan Noccaea caerulescens

Firefly luciferase inhibitor-conjugated peptide quenches bioluminescence: a versatile tool for real time monitoring cellular uptake of biomolecules

First bisphosphonate hydrogelators: potential composers of biocompatible gels

Method for collecting metals

The selective stepwise chemical hydrolysis of alkylcarbonate groups from novel mixed alkylcarbonate trialkyl ester derivatives of etidronic acid

99mTc-labeled partial esters of etidronic acid and their biodistribution in healthy mice

Large glucosylthioureidocalixarenes: selective hosts for mono- and bisphosphonates

Preparation of mixed trialkyl alkylcarbonate derivates of etidronic acid via an unusual route

Systematic study of the physicochemical properties of a homologous series of aminobisphosphonates

A novel strategy for the synthesis of enzymatically stable biotin-DOTA conjugates for in vivo use

Alkylaminobisphosphonates: Synthesis, characterization and determination of pKa-values

Alkylaminobisphosphonates: Synthesis, characterization and determination of pKa-values

Synthesis, Characterization and determination of pKa-values of alkylaminobisphosphonates

Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions

A novel strategy for the preparation of naturally occurring phosphocitrate and its partially esterfied derivatives

Synthesis of novel (1-alkanoyloxy-4-alkanoylaminobutylidene)-1,1-bisphosphonic acid derivatives

Synthesis of novel fatty acid derivatives of etidronic acid

The first synthesis of novel (1-alkoxycarbonyloxyethylidene)-1,1-bisphosphonic acid derivatives taking advantage of the rearrangement characteristic of the tetramethyl ester of etidronate

One-pot synthesis of 1-[(1-phenyl-1-dialkoxyphosphoryl)-methyl]-2-pyrrolidinone

Strategies for the preparation of (1-acetyloxyethylidene)-1,1-bisphosphonic acid derivatives

Design and Synthesis of Novel (I-Hydroxyethylidene)-I, I-Bisphosphonic Acid Derivatives as Possible Prodrugs of Etidronate

First synthesis of etidronate partial amides starting from PCI3

Bisphosphonate prodrugs. Synthesis and identification of (1-hydroxyethylidene)-1,1-bisphosphonic acid tetraesters by mass spectrometry, NMR spectroscopy and X-ray crystallography

Bisphosphonate prodrugs: selective synthesis of (1-hydroxyethylidene)-1,1-bisphosphonate partial esters

Bisphosphonate prodrugs: synthesis and vitro evaluation of alkyl and acyloxymethyl esters of etidronic acid as bioreversible prodrugs of etidronate