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Petri Turhanen

Petri Turhanen

Staff Scientist

Farmasian laitos, Terveystieteiden tiedekunta

[email protected] | 040 355 3857

Tiedot Julkaisut

Tutkimusryhmät

Kuljetinproteiini-välitteinen lääkeaineiden kohde… 01.09.2012 -
Lääkeaine- ja synteesikemian laboratorio 01.01.2010 -
Soveltava kemia 01.01.2012 -

Julkaisut

61/61 kappaletta

Green phosphonate chemistry - Does it exist?
Demadis, Konstantinos D; Adla, Santosh Kumar; Timonen, Juri; Turhanen, Petri A. 2024. Green chemistry. 2025; 27: 863-914 A2 Katsausartikkeli tieteellisessä aikakauslehdessä
TRPA1 Inhibition Effects by 3-Phenylcoumarin Derivatives
Sallomy, Carita; Awolade, Paul; Rahnasto-Rilla, Minna; Hämäläinen, Mari; Nousiainen, Liisa P; Johansson, Niklas G; Hiltunen, Sanna; Turhanen, Petri; Moilanen, Eeva; Lahtela-Kakkonen, Maija; Timonen, Juri M. 2024. Acs medicinal chemistry letters. 15: 1221-1226 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Simple and User-Friendly Methodology for Crystal Water Determination by Quantitative Proton NMR Spectroscopy in Deuterium Oxide
Tynkkynen, Tuulia; Vassaki, Maria; Tiihonen, Tommi E.; Lehto, Vesa-Pekka; Demadis, Konstantinos D.; Turhanen, Petri A.. 2023. Analytical chemistry. 95: 17020-17027 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Structural Diversity in Antiosteolytic Bisphosphonates: Deciphering Structure–Activity Trends in Ultra Long Controlled Release Phenomena
Vassaki, Maria; Hadjicharalambous, Chrystalleni; Turhanen, Petri A.; Demadis, Konstantinos D.. 2023. ACS applied bio materials. 6: 5563-5581 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Surface-Modified Silica Hydrogels for the Programmable Release of Bisphosphonate Anti-Osteoporosis Drugs: The Case of Etidronate
Alatzoglou, Fanouria-Eirini G; Vassaki, Maria; Nirgianaki, Kalliopi; Tripodianos, Eleftherios; Turhanen, Petri; Demadis, Konstantinos D; Papathanasiou, Konstantinos E. 2023. Materials. 16: A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
3-(3-Bromophenyl)-7-acetoxycoumarin
Turhanen, Petri A; Nousiainen, Liisa P; Timonen, Juri M. 2022. Molbank. 2022: A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
6-Bromo-1-hydroxyhexane-1,1-bisphosphonic Acid Monosodium Salt
Turhanen, Petri A. 2022. Molbank. 2022: A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Drug-Inclusive Inorganic–Organic Hybrid Systems for the Controlled Release of the Osteoporosis Drug Zoledronate
Vassaki, Maria; Lazarou, Savvina; Turhanen, Petri; Choquesillo-Lazarte, Duane; Demadis, Konstantinos D. 2022. Molecules. 27: A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Editorial: Phosphonate chemistry in drug design and development, Volume II
Turhanen, Petri A; Kafarski, Pawel. 2022. Frontiers in chemistry. 10: . 1054145 B1 Kirjoitus tieteellisessä aikakauslehdessä
Functionalized nanoporous silicon for extraction of Sc from a leach solution
Rahmani, Arezoo; Thapa, Rinez; Aalto, Juha Matti; Turhanen, Petri; Vepsäläinen, Jouko; Lehto, Vesa Pekka; Riikonen, Joakim. 2022. Hydrometallurgy. 211: . 105866 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Importance of Organophosphorus Compounds in Medicinal Chemistry Field
Turhanen, Petri A. 2022. Journal of biomedical research & environmental sciences. 3: 195-197 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Real-Time On-Site Multielement Analysis of Environmental Waters with a Portable X-ray Fluorescence (pXRF) System
Tiihonen, Tommi E; Nissinen, Tuomo J; Turhanen, Petri A; Vepsäläinen, Jouko J; Riikonen, Joakim; Lehto, Vesa Pekka. 2022. Analytical chemistry. 94: 11739-11744 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Synthesis and Theoretical Studies of Aromatic Azaborines
Hirva, Pipsa; Turhanen, Petri; Timonen, Juri M. 2022. Organics. 3: 196-209 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Synthesis of the biologically important dideuterium-labelled adenosine triphosphate analogue ApppI(d2)
Turhanen, Petri A. 2022. Beilstein journal of organic chemistry. 18: 1466-1470 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä
Calcium and Strontium Coordination Polymers as Controlled Delivery Systems of the Anti-Osteoporosis Drug Risedronate and the Augmenting Effect of Solubilizers
Vassaki, Maria; Kotoula, Christina; Turhanen, Petri; Choquesillo-Lazarte, Duane; Demadis, Konstantinos D.. 2021. Applied sciences
Editorial: Phosphonate Chemistry in Drug Design and Development
Turhanen, Petri A; Demadis, Konstantinos D; Kafarski, Pawel. 2021. Frontiers in chemistry
Meyer-Schuster Rearrangement - Convenient Synthesis of α,ß-Unsaturated α-Iodinated Aldehydes and Ketones
Timonen, Juri M; Turhanen, Petri A. 2021. General chemistry
Plant-based nanostructured silicon carbide modified with bisphosphonates for metal adsorption
Haluska, Ondrej; Rahmani, Arezoo; Salami, Ayobami; Turhanen, Petri; Vepsäläinen, Jouko; Lappalainen, Reijo; Lehto, Vesa-Pekka; Riikonen, Joakim. 2021. Microporous and mesoporous materials
Recovery of uranium with bisphosphonate modified mesoporous silicon
Thapa, Rinez; Rahmani, Arezoo; Turhanen, Petri; Taskinen, Antti; Nissinen, Tuomo; Neitola, Raisa; Vepsäläinen, Jouko; Lehto, Vesa-Pekka; Riikonen, Joakim. 2021. Separation and purification technology
Rapid synthesis of nanostructured porous silicon carbide from biogenic silica
Riikonen, Joakim; Rantanen, Jimi; Thapa, Rinez; Le, Nguyen T; Rigolet, Severinne; Fioux, Philippe; Turhanen, Petri; Bodiford, Nelli K; Kalluri, Jhansi R; lkonen, Timo; Nissinen, Tuomo; Lebeau, Benedicte; Vepsäläinen, Jouko; Coffer, Jeffery L; Lehto, Vesa-Pekka. 2020. Journal of the American Ceramic Society
Self-sacrificial MOFs for ultra-long controlled release of bisphosphonate anti-osteoporotic drugs
Vassaki, Maria; Papathanasiou, Konstantinos; Hadjicharalambous, Chrystalleni; Chandrinou, Daphne; Turhanen, Petri; Choquesillo-Lazarte, Duane; Demadis, Konstantinos. 2020. Chemical communications
The serendipitous discovery of a new green chemistry method
Turhanen, Petri. 2020. Research Outreach
(E)-Di-iodination of Alkynes Using Dried Dowex H+/NaI Approach
Timonen, Juri M; Turhanen, Petri A. 2019. ACS omega
Bisphosphonate modified mesoporous silicon for scandium adsorption
Thapa, Rinez; Nissinen, Tuomo; Turhanen, Petri; Määttä, Juha; Vepsäläinen, Jouko; Lehto, Vesa-Pekka; Riikonen, Joakim. 2019. Microporous and mesoporous materials
Green and Efficient Esterification Method Using Dried Dowex H+/NaI Approach
Turhanen, Petri; Leppänen, Jukka; Vepsäläinen, Jouko J. 2019. ACS omega
Bisphosphonate-Generated ATP-Analogs Inhibit Cell Signaling Pathways
Malwal, SR; O'Dowd, B; Feng, X; Turhanen, PA; Shin, CJ; Yao, J; Kim, BK; Baig, N; Zhou, T; Bansal, S; Khade, R;, Zhang, Y; Oldfield, E. 2018. Journal of the American Chemical Society
Integrated analysis of isopentenyl pyrophosphate (IPP) toxicity in isoprenoid-producing Escherichia coli
George, KW; Thompson, M; Kim, J; Baidoo, EEK; Wang, G; Benites, VT; Petzold, CJ; Chan, LJG; Yilmaz, S; Turhanen, P; Adams, PD; Keasling, JD; Lee, TS. 2018. Metabolic engineering
Phosphorus chemistry: from small molecules, to polymers, to pharmaceutical and industrial applications
Papathanasiou, Konstantinos E; Vassaki, Maria; Spinthaki, Argyro; Alatzoglou, Fanouria-Eirini G; Tripodianos, Eleftherios; Turhanen, Petri; Demadis, Konstantinos D. 2018. Pure and applied chemistry
Selective Calcium-Dependent Inhibition of ATP-Gated P2X3 Receptors by Bisphosphonate-Induced Endogenous ATP Analog ApppI
Ishchenko Y, Shakirzyanova A, Giniatullina R, Skorinkin A, Bart G, Turhanen P, Määttä JA, Mönkkönen J, Giniatullin R. 2017. Journal of pharmacology and experimental therapeutics
Semi-preparative high-performance countercurrent chromatography method for the purification of chemically synthesized ATP analogue, ApppI.
Puljula E, Turhanen PA. 2017. Journal of chromatography b: analytical technologies in the biomedical and life sciences
Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs
Papathanasiou Konstantinos E, Turhanen Petri, Brueckner Stephan I, Brunner Eike, Demadis Konstantinos D. 2017. Scientific reports
Synthesis of a Biologically Important Adenosine Triphosphate Analogue, ApppD
Turhanen Petri. 2017. ACS omega
Preparation of useful building blocks, a-iodo- and bromoalkanols from cyclic ethers using the Dowex H+/NaX (X = I, Br) approach
Turhanen Petri, Vepsäläinen Jouko. 2016. Rsc advances
Synthesis of medronic acid monoesters and their purification by high-performance countercurrent chromatography or by hydroxyapatite
Puljula Elina, Vepsäläinen Jouko, Turhanen Petri. 2016. Beilstein journal of organic chemistry
A powerful tool for acid catalyzed organic addition and substitution reactions
Turhanen Petri, Vepsäläinen Jouko. 2015. Rsc advances
Advanced material and approach for metal ions removal from aqueous solutions
Turhanen Petri A, Vepsäläinen Jouko J, Peräniemi Sirpa. 2015. Scientific reports
Selective acetylation of primary amino groups with phenyl acetate: simple conversion of polyamines into N,N'-diacetyl derivatives
Ucal Sebahat, Khomutov Alex R, Häkkinen Merja R, Turhanen Petri A, Vepsäläinen Jouko J, Weisell Janne. 2015. Arkivoc
Structural Requirements for Bisphosphonate Binding on Hydroxyapatite: NMR Study of Bisphosphonate Partial Esters
Puljula Elina, Turhanen Petri, Vepsäläinen Jouko, Monteil Maelle, Lecouvey Marc, Weisell Janne. 2015. Acs medicinal chemistry letters
Two strategies for the synthesis of the biologically important ATP analogue ApppI, at a multi-milligram scale
Weisell Janne, Vepsäläinen Jouko, Turhanen Petri A. 2015. Beilstein journal of organic chemistry
Synthesis of Triple-Bond-Containing 1-Hydroxy-1,1-bisphosphonic Acid Derivatives To Be Used as Precursors in "Click" Chemistry: Two Examples
Turhanen Petri A. 2014. Journal of organic chemistry
A bisphosphonate increasing the shoot biomass of the metal hyperaccumulator Noccaea caerulescens
Alanne Aino-Liisa, Peräniemi Sirpa, Turhanen Petri, Tuomainen Marjo, Vepsäläinen Jouko, Tervahauta Arja. 2013. Chemosphere
A novel bisphosphonate-based solid phase method for effective removal of chromium(III) from aqueous solutions and tannery effluents
Alanne Aino-Liisa, Tuikka Matti, Tõnsuaadu Kaia, Ylisirniö Markku, Hämäläinen Lea, Turhanen Petri, Vepsäläinen Jouko, Peräniemi Sirpa. 2013. Rsc advances
Firefly luciferase inhibitor-conjugated peptide quenches bioluminescence: a versatile tool for real time monitoring cellular uptake of biomolecules
Poutiainen Pekka K, Rönkkö Teemu, Hinkkanen Ari E, Palvimo Jorma J, Närvänen Ale, Turhanen Petri, Laatikainen Reino, Weisell Janne, Pulkkinen Juha T. 2013. Bioconjugate chemistry
First bisphosphonate hydrogelators: potential composers of biocompatible gels
Alanne Aino-Liisa, Lahtinen Manu, Löfman Miika, Turhanen Petri, Kolehmainen Erkki, Vepsäläinen Jouko, Sievänen Elina. 2013. Journal of materials chemistry. b
The selective stepwise chemical hydrolysis of alkylcarbonate groups from novel mixed alkylcarbonate trialkyl ester derivatives of etidronic acid
Turhanen Petri A, Weisell Janne, Vepsäläinen Jouko J. 2013. Rsc advances
Large glucosylthioureidocalixarenes: selective hosts for mono- and bisphosphonates
Torvinen Mika, Kalenius Elina, Sansone Francesco, Casnati Alessandro, Turhanen Petri, Jänis Janne. 2012. Supramolecular chemistry
Preparation of mixed trialkyl alkylcarbonate derivates of etidronic acid via an unusual route
Turhanen Petri A, Weisell Janne, Vepsäläinen Jouko J. 2012. Beilstein journal of organic chemistry
Systematic study of the physicochemical properties of a homologous series of aminobisphosphonates
Alanne Aino-Liisa, Hyvönen Helena, Lahtinen Manu, Ylisirniö Markku, Turhanen Petri, Kolehmainen Erkki, Peräniemi Sirpa, Vepsäläinen Jouko. 2012. Molecules
A novel strategy for the synthesis of enzymatically stable biotin-DOTA conjugates for in vivo use
Turhanen Petri A, Weisell Janne, Lehtolainen-Dalkilic Pauliina, Määttä Ann-Marie, Vepsäläinen Jouko, Närvänen Ale. 2011. Medchemcomm
Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions
Turhanen PA, Vepsäläinen JJ. 2008. Beilstein journal of organic chemistry
A novel strategy for the preparation of naturally occurring phosphocitrate and its partially esterfied derivatives
Turhanen PA, Demadis KD, Peräniemi S, Vepsäläinen JJ. 2007. Journal of organic chemistry
Synthesis of novel (1-alkanoyloxy-4-alkanoylaminobutylidene)-1,1-bisphosphonic acid derivatives
Turhanen P, Vepsalainen JJ. 2006. Beilstein journal of organic chemistry
Synthesis of novel fatty acid derivatives of etidronic acid
Turhanen PA, Vepsäläinen JJ. 2005. Synthesis: stuttgart
The first synthesis of novel (1-alkoxycarbonyloxyethylidene)-1,1-bisphosphonic acid derivatives taking advantage of the rearrangement characteristic of the tetramethyl ester of etidronate
Turhanen PA, Vepsäläinen JJ. 2005. Synthesis: stuttgart
One-pot synthesis of 1-[(1-phenyl-1-dialkoxyphosphoryl)-methyl]-2-pyrrolidinone
Turhanen PA, Soininen P, Vepsäläinen JJ. 2004. Letters in organic chemistry
Strategies for the preparation of (1-acetyloxyethylidene)-1,1-bisphosphonic acid derivatives
Turhanen PA, Vepsäläinen JJ. 2004. Synthesis: stuttgart
Design and Synthesis of Novel (I-Hydroxyethylidene)-I, I-Bisphosphonic Acid Derivatives as Possible Prodrugs of Etidronate
Turhanen P. 2003. Kuopion yliopiston julkaisuja C. Luonnontieteet ja ympäristötieteet
First synthesis of etidronate partial amides starting from PCI3
Turhanen PA, Niemi R, Peräkylä M, Järvinen T, Vepsäläinen JJ. 2003. Organic and biomolecular chemistry
Bisphosphonate prodrugs. Synthesis and identification of (1-hydroxyethylidene)-1,1-bisphosphonic acid tetraesters by mass spectrometry, NMR spectroscopy and X-ray crystallography
Turhanen PA, Ahlgren MJ, Järvinen T, Vepsäläinen JJ. 2001. PHOSPHORUS, SULFUR, AND SILICON AND THE RELATED ELEMENTS
Bisphosphonate prodrugs: selective synthesis of (1-hydroxyethylidene)-1,1-bisphosphonate partial esters
Turhanen PA, Ahlgren MJ, Järvinen T, Vepsäläinen J. 2001. Synthesis: stuttgart
Bisphosphonate prodrugs: synthesis and vitro evaluation of alkyl and acyloxymethyl esters of etidronic acid as bioreversible prodrugs of etidronate
Niemi R, Turhanen P, Vepsäläinen J, Taipale H, Järvinen T. 2000. European journal of pharmaceutical sciences

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Näytä asetukset

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Tarkenna hakuasi

Petri Turhanen

Tutkimusryhmät

Green phosphonate chemistry - Does it exist?

TRPA1 Inhibition Effects by 3-Phenylcoumarin Derivatives

Simple and User-Friendly Methodology for Crystal Water Determination by Quantitative Proton NMR Spectroscopy in Deuterium Oxide

Structural Diversity in Antiosteolytic Bisphosphonates: Deciphering Structure–Activity Trends in Ultra Long Controlled Release Phenomena

Surface-Modified Silica Hydrogels for the Programmable Release of Bisphosphonate Anti-Osteoporosis Drugs: The Case of Etidronate

3-(3-Bromophenyl)-7-acetoxycoumarin

6-Bromo-1-hydroxyhexane-1,1-bisphosphonic Acid Monosodium Salt

Drug-Inclusive Inorganic–Organic Hybrid Systems for the Controlled Release of the Osteoporosis Drug Zoledronate

Editorial: Phosphonate chemistry in drug design and development, Volume II

Functionalized nanoporous silicon for extraction of Sc from a leach solution

Importance of Organophosphorus Compounds in Medicinal Chemistry Field

Real-Time On-Site Multielement Analysis of Environmental Waters with a Portable X-ray Fluorescence (pXRF) System

Synthesis and Theoretical Studies of Aromatic Azaborines

Synthesis of the biologically important dideuterium-labelled adenosine triphosphate analogue ApppI(d2)

Calcium and Strontium Coordination Polymers as Controlled Delivery Systems of the Anti-Osteoporosis Drug Risedronate and the Augmenting Effect of Solubilizers

Editorial: Phosphonate Chemistry in Drug Design and Development

Meyer-Schuster Rearrangement - Convenient Synthesis of α,ß-Unsaturated α-Iodinated Aldehydes and Ketones

Plant-based nanostructured silicon carbide modified with bisphosphonates for metal adsorption

Recovery of uranium with bisphosphonate modified mesoporous silicon

Rapid synthesis of nanostructured porous silicon carbide from biogenic silica

Self-sacrificial MOFs for ultra-long controlled release of bisphosphonate anti-osteoporotic drugs

The serendipitous discovery of a new green chemistry method

(E)-Di-iodination of Alkynes Using Dried Dowex H+/NaI Approach

Bisphosphonate modified mesoporous silicon for scandium adsorption

Green and Efficient Esterification Method Using Dried Dowex H+/NaI Approach

Bisphosphonate-Generated ATP-Analogs Inhibit Cell Signaling Pathways

Integrated analysis of isopentenyl pyrophosphate (IPP) toxicity in isoprenoid-producing Escherichia coli

Phosphorus chemistry: from small molecules, to polymers, to pharmaceutical and industrial applications

Selective Calcium-Dependent Inhibition of ATP-Gated P2X3 Receptors by Bisphosphonate-Induced Endogenous ATP Analog ApppI

Semi-preparative high-performance countercurrent chromatography method for the purification of chemically synthesized ATP analogue, ApppI.

Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs

Synthesis of a Biologically Important Adenosine Triphosphate Analogue, ApppD

Preparation of useful building blocks, a-iodo- and bromoalkanols from cyclic ethers using the Dowex H+/NaX (X = I, Br) approach

Synthesis of medronic acid monoesters and their purification by high-performance countercurrent chromatography or by hydroxyapatite

A powerful tool for acid catalyzed organic addition and substitution reactions

Advanced material and approach for metal ions removal from aqueous solutions

Selective acetylation of primary amino groups with phenyl acetate: simple conversion of polyamines into N,N'-diacetyl derivatives

Structural Requirements for Bisphosphonate Binding on Hydroxyapatite: NMR Study of Bisphosphonate Partial Esters

Two strategies for the synthesis of the biologically important ATP analogue ApppI, at a multi-milligram scale

Synthesis of Triple-Bond-Containing 1-Hydroxy-1,1-bisphosphonic Acid Derivatives To Be Used as Precursors in "Click" Chemistry: Two Examples

A bisphosphonate increasing the shoot biomass of the metal hyperaccumulator Noccaea caerulescens

A novel bisphosphonate-based solid phase method for effective removal of chromium(III) from aqueous solutions and tannery effluents

Firefly luciferase inhibitor-conjugated peptide quenches bioluminescence: a versatile tool for real time monitoring cellular uptake of biomolecules

First bisphosphonate hydrogelators: potential composers of biocompatible gels

The selective stepwise chemical hydrolysis of alkylcarbonate groups from novel mixed alkylcarbonate trialkyl ester derivatives of etidronic acid

Large glucosylthioureidocalixarenes: selective hosts for mono- and bisphosphonates

Preparation of mixed trialkyl alkylcarbonate derivates of etidronic acid via an unusual route

Systematic study of the physicochemical properties of a homologous series of aminobisphosphonates

A novel strategy for the synthesis of enzymatically stable biotin-DOTA conjugates for in vivo use

Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions

A novel strategy for the preparation of naturally occurring phosphocitrate and its partially esterfied derivatives

Synthesis of novel (1-alkanoyloxy-4-alkanoylaminobutylidene)-1,1-bisphosphonic acid derivatives

Synthesis of novel fatty acid derivatives of etidronic acid

The first synthesis of novel (1-alkoxycarbonyloxyethylidene)-1,1-bisphosphonic acid derivatives taking advantage of the rearrangement characteristic of the tetramethyl ester of etidronate

One-pot synthesis of 1-[(1-phenyl-1-dialkoxyphosphoryl)-methyl]-2-pyrrolidinone

Strategies for the preparation of (1-acetyloxyethylidene)-1,1-bisphosphonic acid derivatives

Design and Synthesis of Novel (I-Hydroxyethylidene)-I, I-Bisphosphonic Acid Derivatives as Possible Prodrugs of Etidronate

First synthesis of etidronate partial amides starting from PCI3

Bisphosphonate prodrugs. Synthesis and identification of (1-hydroxyethylidene)-1,1-bisphosphonic acid tetraesters by mass spectrometry, NMR spectroscopy and X-ray crystallography

Bisphosphonate prodrugs: selective synthesis of (1-hydroxyethylidene)-1,1-bisphosphonate partial esters

Bisphosphonate prodrugs: synthesis and vitro evaluation of alkyl and acyloxymethyl esters of etidronic acid as bioreversible prodrugs of etidronate