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Petri Turhanen

Petri Turhanen

Staff Scientist

School of Pharmacy, Faculty of Health Sciences

petri.turhanen@uef.fi | +358 40 355 3857

Information Publications

Research groups

Transporter-Targeted Drug Delivery 01.09.2012 -
Medicinal chemistry and organic synthesis facilit… 01.01.2010 -
Applied chemistry 01.01.2012 -

Publications

70/70 items

TRPA1 Inhibition Effects by 3-Phenylcoumarin Derivatives
Sallomy, Carita; Awolade, Paul; Rahnasto-Rilla, Minna; Hämäläinen, Mari; Nousiainen, Liisa P; Johansson, Niklas G; Hiltunen, Sanna; Turhanen, Petri; Moilanen, Eeva; Lahtela-Kakkonen, Maija; Timonen, Juri M. 2024. Acs medicinal chemistry letters. 15: 1221-1226 A1 Journal article (refereed), original research
Simple and User-Friendly Methodology for Crystal Water Determination by Quantitative Proton NMR Spectroscopy in Deuterium Oxide
Tynkkynen, Tuulia; Vassaki, Maria; Tiihonen, Tommi E.; Lehto, Vesa-Pekka; Demadis, Konstantinos D.; Turhanen, Petri A.. 2023. Analytical chemistry. 95: 17020-17027 A1 Journal article (refereed), original research
Structural Diversity in Antiosteolytic Bisphosphonates: Deciphering Structure–Activity Trends in Ultra Long Controlled Release Phenomena
Vassaki, Maria; Hadjicharalambous, Chrystalleni; Turhanen, Petri A.; Demadis, Konstantinos D.. 2023. ACS applied bio materials. 6: 5563-5581 A1 Journal article (refereed), original research
Surface-Modified Silica Hydrogels for the Programmable Release of Bisphosphonate Anti-Osteoporosis Drugs: The Case of Etidronate
Alatzoglou, Fanouria-Eirini G; Vassaki, Maria; Nirgianaki, Kalliopi; Tripodianos, Eleftherios; Turhanen, Petri; Demadis, Konstantinos D; Papathanasiou, Konstantinos E. 2023. Materials. 16: A1 Journal article (refereed), original research
3-(3-Bromophenyl)-7-acetoxycoumarin
Turhanen, Petri A; Nousiainen, Liisa P; Timonen, Juri M. 2022. Molbank. 2022: A1 Journal article (refereed), original research
6-Bromo-1-hydroxyhexane-1,1-bisphosphonic Acid Monosodium Salt
Turhanen, Petri A. 2022. Molbank. 2022: A1 Journal article (refereed), original research
Drug-Inclusive Inorganic–Organic Hybrid Systems for the Controlled Release of the Osteoporosis Drug Zoledronate
Vassaki, Maria; Lazarou, Savvina; Turhanen, Petri; Choquesillo-Lazarte, Duane; Demadis, Konstantinos D. 2022. Molecules. 27: A1 Journal article (refereed), original research
Editorial: Phosphonate chemistry in drug design and development, Volume II
Turhanen, Petri A; Kafarski, Pawel. 2022. Frontiers in chemistry. 10: . 1054145 B1 Non-refereed journal articles
Functionalized nanoporous silicon for extraction of Sc from a leach solution
Rahmani, Arezoo; Thapa, Rinez; Aalto, Juha Matti; Turhanen, Petri; Vepsäläinen, Jouko; Lehto, Vesa Pekka; Riikonen, Joakim. 2022. Hydrometallurgy. 211: . 105866 A1 Journal article (refereed), original research
Importance of Organophosphorus Compounds in Medicinal Chemistry Field
Turhanen, Petri A. 2022. Journal of biomedical research & environmental sciences. 3: 195-197 A1 Journal article (refereed), original research
Real-Time On-Site Multielement Analysis of Environmental Waters with a Portable X-ray Fluorescence (pXRF) System
Tiihonen, Tommi E; Nissinen, Tuomo J; Turhanen, Petri A; Vepsäläinen, Jouko J; Riikonen, Joakim; Lehto, Vesa Pekka. 2022. Analytical chemistry. 94: 11739-11744 A1 Journal article (refereed), original research
Synthesis and Theoretical Studies of Aromatic Azaborines
Hirva, Pipsa; Turhanen, Petri; Timonen, Juri M. 2022. Organics. 3: 196-209 A1 Journal article (refereed), original research
Synthesis of the biologically important dideuterium-labelled adenosine triphosphate analogue ApppI(d2)
Turhanen, Petri A. 2022. Beilstein journal of organic chemistry. 18: 1466-1470 A1 Journal article (refereed), original research
Calcium and Strontium Coordination Polymers as Controlled Delivery Systems of the Anti-Osteoporosis Drug Risedronate and the Augmenting Effect of Solubilizers
Vassaki, Maria; Kotoula, Christina; Turhanen, Petri; Choquesillo-Lazarte, Duane; Demadis, Konstantinos D.. 2021. Applied sciences. 11: 11383 A1 Journal article (refereed), original research
Editorial: Phosphonate Chemistry in Drug Design and Development
Turhanen, Petri A; Demadis, Konstantinos D; Kafarski, Pawel. 2021. Frontiers in chemistry. 9: 695128 B1 Non-refereed journal articles
Meyer-Schuster Rearrangement - Convenient Synthesis of α,ß-Unsaturated α-Iodinated Aldehydes and Ketones
Timonen, Juri M; Turhanen, Petri A. 2021. General chemistry. 7: 200023 A1 Journal article (refereed), original research
Plant-based nanostructured silicon carbide modified with bisphosphonates for metal adsorption
Haluska, Ondrej; Rahmani, Arezoo; Salami, Ayobami; Turhanen, Petri; Vepsäläinen, Jouko; Lappalainen, Reijo; Lehto, Vesa-Pekka; Riikonen, Joakim. 2021. Microporous and mesoporous materials. 324: 111294 A1 Journal article (refereed), original research
Recovery of uranium with bisphosphonate modified mesoporous silicon
Thapa, Rinez; Rahmani, Arezoo; Turhanen, Petri; Taskinen, Antti; Nissinen, Tuomo; Neitola, Raisa; Vepsäläinen, Jouko; Lehto, Vesa-Pekka; Riikonen, Joakim. 2021. Separation and purification technology. 272: 118913 A1 Journal article (refereed), original research
Rapid synthesis of nanostructured porous silicon carbide from biogenic silica
Riikonen, Joakim; Rantanen, Jimi; Thapa, Rinez; Le, Nguyen T; Rigolet, Severinne; Fioux, Philippe; Turhanen, Petri; Bodiford, Nelli K; Kalluri, Jhansi R; lkonen, Timo; Nissinen, Tuomo; Lebeau, Benedicte; Vepsäläinen, Jouko; Coffer, Jeffery L; Lehto, Vesa-Pekka. 2020. Journal of the American Ceramic Society. 2021; 104: 766-775 A1 Journal article (refereed), original research
Self-sacrificial MOFs for ultra-long controlled release of bisphosphonate anti-osteoporotic drugs
Vassaki, Maria; Papathanasiou, Konstantinos; Hadjicharalambous, Chrystalleni; Chandrinou, Daphne; Turhanen, Petri; Choquesillo-Lazarte, Duane; Demadis, Konstantinos. 2020. Chemical communications. 56: 5166-5169 A1 Journal article (refereed), original research
The serendipitous discovery of a new green chemistry method
Turhanen, Petri. 2020. Research Outreach. : 6-9 B1 Non-refereed journal articles
(E)-Di-iodination of Alkynes Using Dried Dowex H+/NaI Approach
Timonen, Juri M; Turhanen, Petri A. 2019. ACS omega. 4: 14663-14668 A1 Journal article (refereed), original research
Bisphosphonate modified mesoporous silicon for scandium adsorption
Thapa, Rinez; Nissinen, Tuomo; Turhanen, Petri; Määttä, Juha; Vepsäläinen, Jouko; Lehto, Vesa-Pekka; Riikonen, Joakim. 2019. Microporous and mesoporous materials. 2020; 296: 109980 A1 Journal article (refereed), original research
Green and Efficient Esterification Method Using Dried Dowex H+/NaI Approach
Turhanen, Petri; Leppänen, Jukka; Vepsäläinen, Jouko J. 2019. ACS omega. 4: 8974-8984 A1 Journal article (refereed), original research
Bisphosphonate-Generated ATP-Analogs Inhibit Cell Signaling Pathways
Malwal, SR; O'Dowd, B; Feng, X; Turhanen, PA; Shin, CJ; Yao, J; Kim, BK; Baig, N; Zhou, T; Bansal, S; Khade, R;, Zhang, Y; Oldfield, E. 2018. Journal of the American Chemical Society. 140: 7568-7578 A1 Journal article (refereed), original research
Integrated analysis of isopentenyl pyrophosphate (IPP) toxicity in isoprenoid-producing Escherichia coli
George, KW; Thompson, M; Kim, J; Baidoo, EEK; Wang, G; Benites, VT; Petzold, CJ; Chan, LJG; Yilmaz, S; Turhanen, P; Adams, PD; Keasling, JD; Lee, TS. 2018. Metabolic engineering. 47: 60-72 A1 Journal article (refereed), original research
Phosphorus chemistry: from small molecules, to polymers, to pharmaceutical and industrial applications
Papathanasiou, Konstantinos E; Vassaki, Maria; Spinthaki, Argyro; Alatzoglou, Fanouria-Eirini G; Tripodianos, Eleftherios; Turhanen, Petri; Demadis, Konstantinos D. 2018. Pure and applied chemistry. 2019; 91: 421-4411-21 A1 Journal article (refereed), original research
Selective Calcium-Dependent Inhibition of ATP-Gated P2X3 Receptors by Bisphosphonate-Induced Endogenous ATP Analog ApppI
Ishchenko Y, Shakirzyanova A, Giniatullina R, Skorinkin A, Bart G, Turhanen P, Määttä JA, Mönkkönen J, Giniatullin R. 2017. Journal of pharmacology and experimental therapeutics. 361: 472-481 A1 Journal article (refereed), original research
Semi-preparative high-performance countercurrent chromatography method for the purification of chemically synthesized ATP analogue, ApppI.
Puljula E, Turhanen PA. 2017. Journal of chromatography b: analytical technologies in the biomedical and life sciences. 1063: 180-182 A1 Journal article (refereed), original research
Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs
Papathanasiou Konstantinos E, Turhanen Petri, Brueckner Stephan I, Brunner Eike, Demadis Konstantinos D. 2017. Scientific reports. 7: 4743 A1 Journal article (refereed), original research
Synthesis of a Biologically Important Adenosine Triphosphate Analogue, ApppD
Turhanen Petri. 2017. ACS omega. 2: 2835-2838 A1 Journal article (refereed), original research
Preparation of useful building blocks, a-iodo- and bromoalkanols from cyclic ethers using the Dowex H+/NaX (X = I, Br) approach
Turhanen Petri, Vepsäläinen Jouko. 2016. Rsc advances. 6: 15937-15940 A1 Journal article (refereed), original research
Synthesis of medronic acid monoesters and their purification by high-performance countercurrent chromatography or by hydroxyapatite
Puljula Elina, Vepsäläinen Jouko, Turhanen Petri. 2016. Beilstein journal of organic chemistry. 12: 2145-2149 A1 Journal article (refereed), original research
A powerful tool for acid catalyzed organic addition and substitution reactions
Turhanen Petri, Vepsäläinen Jouko. 2015. Rsc advances. 5: 26218-26222 A1 Journal article (refereed), original research
Advanced material and approach for metal ions removal from aqueous solutions
Turhanen Petri A, Vepsäläinen Jouko J, Peräniemi Sirpa. 2015. Scientific reports. 5: 8992 A1 Journal article (refereed), original research
Selective acetylation of primary amino groups with phenyl acetate: simple conversion of polyamines into N,N'-diacetyl derivatives
Ucal Sebahat, Khomutov Alex R, Häkkinen Merja R, Turhanen Petri A, Vepsäläinen Jouko J, Weisell Janne. 2015. Arkivoc. 2015: 42-49 A1 Journal article (refereed), original research
Structural Requirements for Bisphosphonate Binding on Hydroxyapatite: NMR Study of Bisphosphonate Partial Esters
Puljula Elina, Turhanen Petri, Vepsäläinen Jouko, Monteil Maelle, Lecouvey Marc, Weisell Janne. 2015. Acs medicinal chemistry letters. 6: 397-401 A1 Journal article (refereed), original research
Two strategies for the synthesis of the biologically important ATP analogue ApppI, at a multi-milligram scale
Weisell Janne, Vepsäläinen Jouko, Turhanen Petri A. 2015. Beilstein journal of organic chemistry. 11: 2189-2193 A1 Journal article (refereed), original research
Uusi menetelmä ja uusi katalyyttinen järjestelmä selektiivisiin orgaanisiin additio- ja substituutioreaktioihin
Vepsäläinen Jouko, Turhanen Petri. 2015. H1 Granted patent
Bisphosphonates: How does the structure affect the ability to bind to hydroxyapatite?
Elina Puljula, Aino-Liisa Alanne, Petri Turhanen, Jouko Vepsäläinen, Janne Weisell. 2014.
Synthesis of Triple-Bond-Containing 1-Hydroxy-1,1-bisphosphonic Acid Derivatives To Be Used as Precursors in "Click" Chemistry: Two Examples
Turhanen Petri A. 2014. Journal of organic chemistry. 79: 6330-6335 A1 Journal article (refereed), original research
A bisphosphonate increasing the shoot biomass of the metal hyperaccumulator Noccaea caerulescens
Alanne Aino-Liisa, Peräniemi Sirpa, Turhanen Petri, Tuomainen Marjo, Vepsäläinen Jouko, Tervahauta Arja. 2013. Chemosphere. 2014:95: 566-571 A1 Journal article (refereed), original research
A novel bisphosphonate-based solid phase method for effective removal of chromium(III) from aqueous solutions and tannery effluents
Alanne Aino-Liisa, Tuikka Matti, Tõnsuaadu Kaia, Ylisirniö Markku, Hämäläinen Lea, Turhanen Petri, Vepsäläinen Jouko, Peräniemi Sirpa. 2013. Rsc advances. 3: 14132-14138 A1 Journal article (refereed), original research
An Insoluble Bisphosphonate as a Metal Collector - an Innovative Solution to the Waste Water Problems of the Mining Industry
Aino-Liisa Alanne, Petri Turhanen, Janne Kankkunen, Sirpa Peräniemi, Jouko Vepsäläinen. 2013.
An in vitro method for determining bisphosphonate-binding to hydroxyapatite by 31P NMR
Sankala, E., Alanne, A.-L., Turhanen, P., Weisell, J. and Vepsäläinen.. 2013.
Effect of bisphosphonates on metal accumulation in the metal hyperaccumulator plan Noccaea caerulescens
Alanne A, Tuomainen M, Turhanen P, Peräniemi S, Vepsäläinen J, Kärenlmpi S, Tervahauta A. 2013.
Firefly luciferase inhibitor-conjugated peptide quenches bioluminescence: a versatile tool for real time monitoring cellular uptake of biomolecules
Poutiainen Pekka K, Rönkkö Teemu, Hinkkanen Ari E, Palvimo Jorma J, Närvänen Ale, Turhanen Petri, Laatikainen Reino, Weisell Janne, Pulkkinen Juha T. 2013. Bioconjugate chemistry. 2014:25: 4-10 A1 Journal article (refereed), original research
First bisphosphonate hydrogelators: potential composers of biocompatible gels
Alanne Aino-Liisa, Lahtinen Manu, Löfman Miika, Turhanen Petri, Kolehmainen Erkki, Vepsäläinen Jouko, Sievänen Elina. 2013. Journal of materials chemistry. b. 1: 6201-6212 A1 Journal article (refereed), original research
Method for collecting metals
Turhanen Petri, Peräniemi Sirpa, Vepsäläinen Jouko. 2013. H1 Granted patent
The selective stepwise chemical hydrolysis of alkylcarbonate groups from novel mixed alkylcarbonate trialkyl ester derivatives of etidronic acid
Turhanen Petri A, Weisell Janne, Vepsäläinen Jouko J. 2013. Rsc advances. 3: 2417-2421 A1 Journal article (refereed), original research
99mTc-labeled partial esters of etidronic acid and their biodistribution in healthy mice
Sankala E, Turhanen P, Weisell J, Monteil M, Lecouvey M, Huhtala T, Närvänen A, Vepsäläinen J. 2012.
Large glucosylthioureidocalixarenes: selective hosts for mono- and bisphosphonates
Torvinen Mika, Kalenius Elina, Sansone Francesco, Casnati Alessandro, Turhanen Petri, Jänis Janne. 2012. Supramolecular chemistry. 24: 228-233 A1 Journal article (refereed), original research
Preparation of mixed trialkyl alkylcarbonate derivates of etidronic acid via an unusual route
Turhanen Petri A, Weisell Janne, Vepsäläinen Jouko J. 2012. Beilstein journal of organic chemistry. 8: 2019-2024 A1 Journal article (refereed), original research
Systematic study of the physicochemical properties of a homologous series of aminobisphosphonates
Alanne Aino-Liisa, Hyvönen Helena, Lahtinen Manu, Ylisirniö Markku, Turhanen Petri, Kolehmainen Erkki, Peräniemi Sirpa, Vepsäläinen Jouko. 2012. Molecules. 17: 10928-10945 A1 Journal article (refereed), original research
A novel strategy for the synthesis of enzymatically stable biotin-DOTA conjugates for in vivo use
Turhanen Petri A, Weisell Janne, Lehtolainen-Dalkilic Pauliina, Määttä Ann-Marie, Vepsäläinen Jouko, Närvänen Ale. 2011. Medchemcomm. 2: 886-888 A1 Journal article (refereed), original research
Alkylaminobisphosphonates: Synthesis, characterization and determination of pKa-values
Saari, A-L.; Ylisirniö, M.; Lahtinen, M.; Hyvönen, H.; Turhanen, P.; Kolehmainen, E.; Peräniemi, S. and Vepsäläinen, J.. 2011.
Alkylaminobisphosphonates: Synthesis, characterization and determination of pKa-values
Saari, A-L.; Ylisirniö, M.; Lahtinen, M.; Hyvönen, H.; Turhanen, P.; Kolehmainen, E.; Peräniemi, S. and Vepsäläinen, J.. 2011.
Synthesis, Characterization and determination of pKa-values of alkylaminobisphosphonates
Saari Aino-Liisa, Ylisirniö, Markku, Lahtinen Manu, Hyvönen Helena, Turhanen Petri, Kolehmainen Erkki, Peräniemi Sirpa, Vepsäläinen Jouko. 2011.
Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions
Turhanen PA, Vepsäläinen JJ. 2008. Beilstein journal of organic chemistry. 4: A1 Journal article (refereed), original research
A novel strategy for the preparation of naturally occurring phosphocitrate and its partially esterfied derivatives
Turhanen PA, Demadis KD, Peräniemi S, Vepsäläinen JJ. 2007. Journal of organic chemistry. 72: 1468-1471 A1 Journal article (refereed), original research
Synthesis of novel (1-alkanoyloxy-4-alkanoylaminobutylidene)-1,1-bisphosphonic acid derivatives
Turhanen P, Vepsalainen JJ. 2006. Beilstein journal of organic chemistry. 2:2: A1 Journal article (refereed), original research
Synthesis of novel fatty acid derivatives of etidronic acid
Turhanen PA, Vepsäläinen JJ. 2005. Synthesis: stuttgart. : 3063-3066 A1 Journal article (refereed), original research
The first synthesis of novel (1-alkoxycarbonyloxyethylidene)-1,1-bisphosphonic acid derivatives taking advantage of the rearrangement characteristic of the tetramethyl ester of etidronate
Turhanen PA, Vepsäläinen JJ. 2005. Synthesis: stuttgart. : 2119-2121 A1 Journal article (refereed), original research
One-pot synthesis of 1-[(1-phenyl-1-dialkoxyphosphoryl)-methyl]-2-pyrrolidinone
Turhanen PA, Soininen P, Vepsäläinen JJ. 2004. Letters in organic chemistry. : 343-345 A1 Journal article (refereed), original research
Strategies for the preparation of (1-acetyloxyethylidene)-1,1-bisphosphonic acid derivatives
Turhanen PA, Vepsäläinen JJ. 2004. Synthesis: stuttgart. : 0992-0994 A1 Journal article (refereed), original research
Design and Synthesis of Novel (I-Hydroxyethylidene)-I, I-Bisphosphonic Acid Derivatives as Possible Prodrugs of Etidronate
Turhanen P. 2003. Kuopion yliopiston julkaisuja C. Luonnontieteet ja ympäristötieteet G5 Doctoral dissertation (article)
First synthesis of etidronate partial amides starting from PCI3
Turhanen PA, Niemi R, Peräkylä M, Järvinen T, Vepsäläinen JJ. 2003. Organic and biomolecular chemistry. 1: 3223-3226 A1 Journal article (refereed), original research
Bisphosphonate prodrugs. Synthesis and identification of (1-hydroxyethylidene)-1,1-bisphosphonic acid tetraesters by mass spectrometry, NMR spectroscopy and X-ray crystallography
Turhanen PA, Ahlgren MJ, Järvinen T, Vepsäläinen JJ. 2001. PHOSPHORUS, SULFUR, AND SILICON AND THE RELATED ELEMENTS. 170: 115-133 A1 Journal article (refereed), original research
Bisphosphonate prodrugs: selective synthesis of (1-hydroxyethylidene)-1,1-bisphosphonate partial esters
Turhanen PA, Ahlgren MJ, Järvinen T, Vepsäläinen J. 2001. Synthesis: stuttgart. : 633-637 A1 Journal article (refereed), original research
Bisphosphonate prodrugs: synthesis and vitro evaluation of alkyl and acyloxymethyl esters of etidronic acid as bioreversible prodrugs of etidronate
Niemi R, Turhanen P, Vepsäläinen J, Taipale H, Järvinen T. 2000. European journal of pharmaceutical sciences. 11: 173-180 A1 Journal article (refereed), original research

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Petri Turhanen

Research groups

TRPA1 Inhibition Effects by 3-Phenylcoumarin Derivatives

Simple and User-Friendly Methodology for Crystal Water Determination by Quantitative Proton NMR Spectroscopy in Deuterium Oxide

Structural Diversity in Antiosteolytic Bisphosphonates: Deciphering Structure–Activity Trends in Ultra Long Controlled Release Phenomena

Surface-Modified Silica Hydrogels for the Programmable Release of Bisphosphonate Anti-Osteoporosis Drugs: The Case of Etidronate

3-(3-Bromophenyl)-7-acetoxycoumarin

6-Bromo-1-hydroxyhexane-1,1-bisphosphonic Acid Monosodium Salt

Drug-Inclusive Inorganic–Organic Hybrid Systems for the Controlled Release of the Osteoporosis Drug Zoledronate

Editorial: Phosphonate chemistry in drug design and development, Volume II

Functionalized nanoporous silicon for extraction of Sc from a leach solution

Importance of Organophosphorus Compounds in Medicinal Chemistry Field

Real-Time On-Site Multielement Analysis of Environmental Waters with a Portable X-ray Fluorescence (pXRF) System

Synthesis and Theoretical Studies of Aromatic Azaborines

Synthesis of the biologically important dideuterium-labelled adenosine triphosphate analogue ApppI(d2)

Calcium and Strontium Coordination Polymers as Controlled Delivery Systems of the Anti-Osteoporosis Drug Risedronate and the Augmenting Effect of Solubilizers

Editorial: Phosphonate Chemistry in Drug Design and Development

Meyer-Schuster Rearrangement - Convenient Synthesis of α,ß-Unsaturated α-Iodinated Aldehydes and Ketones

Plant-based nanostructured silicon carbide modified with bisphosphonates for metal adsorption

Recovery of uranium with bisphosphonate modified mesoporous silicon

Rapid synthesis of nanostructured porous silicon carbide from biogenic silica

Self-sacrificial MOFs for ultra-long controlled release of bisphosphonate anti-osteoporotic drugs

The serendipitous discovery of a new green chemistry method

(E)-Di-iodination of Alkynes Using Dried Dowex H+/NaI Approach

Bisphosphonate modified mesoporous silicon for scandium adsorption

Green and Efficient Esterification Method Using Dried Dowex H+/NaI Approach

Bisphosphonate-Generated ATP-Analogs Inhibit Cell Signaling Pathways

Integrated analysis of isopentenyl pyrophosphate (IPP) toxicity in isoprenoid-producing Escherichia coli

Phosphorus chemistry: from small molecules, to polymers, to pharmaceutical and industrial applications

Selective Calcium-Dependent Inhibition of ATP-Gated P2X3 Receptors by Bisphosphonate-Induced Endogenous ATP Analog ApppI

Semi-preparative high-performance countercurrent chromatography method for the purification of chemically synthesized ATP analogue, ApppI.

Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs

Synthesis of a Biologically Important Adenosine Triphosphate Analogue, ApppD

Preparation of useful building blocks, a-iodo- and bromoalkanols from cyclic ethers using the Dowex H+/NaX (X = I, Br) approach

Synthesis of medronic acid monoesters and their purification by high-performance countercurrent chromatography or by hydroxyapatite

A powerful tool for acid catalyzed organic addition and substitution reactions

Advanced material and approach for metal ions removal from aqueous solutions

Selective acetylation of primary amino groups with phenyl acetate: simple conversion of polyamines into N,N'-diacetyl derivatives

Structural Requirements for Bisphosphonate Binding on Hydroxyapatite: NMR Study of Bisphosphonate Partial Esters

Two strategies for the synthesis of the biologically important ATP analogue ApppI, at a multi-milligram scale

Uusi menetelmä ja uusi katalyyttinen järjestelmä selektiivisiin orgaanisiin additio- ja substituutioreaktioihin

Bisphosphonates: How does the structure affect the ability to bind to hydroxyapatite?

Synthesis of Triple-Bond-Containing 1-Hydroxy-1,1-bisphosphonic Acid Derivatives To Be Used as Precursors in "Click" Chemistry: Two Examples

A bisphosphonate increasing the shoot biomass of the metal hyperaccumulator Noccaea caerulescens

A novel bisphosphonate-based solid phase method for effective removal of chromium(III) from aqueous solutions and tannery effluents

An Insoluble Bisphosphonate as a Metal Collector - an Innovative Solution to the Waste Water Problems of the Mining Industry

An in vitro method for determining bisphosphonate-binding to hydroxyapatite by 31P NMR

Effect of bisphosphonates on metal accumulation in the metal hyperaccumulator plan Noccaea caerulescens

Firefly luciferase inhibitor-conjugated peptide quenches bioluminescence: a versatile tool for real time monitoring cellular uptake of biomolecules

First bisphosphonate hydrogelators: potential composers of biocompatible gels

Method for collecting metals

The selective stepwise chemical hydrolysis of alkylcarbonate groups from novel mixed alkylcarbonate trialkyl ester derivatives of etidronic acid

99mTc-labeled partial esters of etidronic acid and their biodistribution in healthy mice

Large glucosylthioureidocalixarenes: selective hosts for mono- and bisphosphonates

Preparation of mixed trialkyl alkylcarbonate derivates of etidronic acid via an unusual route

Systematic study of the physicochemical properties of a homologous series of aminobisphosphonates

A novel strategy for the synthesis of enzymatically stable biotin-DOTA conjugates for in vivo use

Alkylaminobisphosphonates: Synthesis, characterization and determination of pKa-values

Alkylaminobisphosphonates: Synthesis, characterization and determination of pKa-values

Synthesis, Characterization and determination of pKa-values of alkylaminobisphosphonates

Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions

A novel strategy for the preparation of naturally occurring phosphocitrate and its partially esterfied derivatives

Synthesis of novel (1-alkanoyloxy-4-alkanoylaminobutylidene)-1,1-bisphosphonic acid derivatives

Synthesis of novel fatty acid derivatives of etidronic acid

The first synthesis of novel (1-alkoxycarbonyloxyethylidene)-1,1-bisphosphonic acid derivatives taking advantage of the rearrangement characteristic of the tetramethyl ester of etidronate

One-pot synthesis of 1-[(1-phenyl-1-dialkoxyphosphoryl)-methyl]-2-pyrrolidinone

Strategies for the preparation of (1-acetyloxyethylidene)-1,1-bisphosphonic acid derivatives

Design and Synthesis of Novel (I-Hydroxyethylidene)-I, I-Bisphosphonic Acid Derivatives as Possible Prodrugs of Etidronate

First synthesis of etidronate partial amides starting from PCI3

Bisphosphonate prodrugs. Synthesis and identification of (1-hydroxyethylidene)-1,1-bisphosphonic acid tetraesters by mass spectrometry, NMR spectroscopy and X-ray crystallography

Bisphosphonate prodrugs: selective synthesis of (1-hydroxyethylidene)-1,1-bisphosphonate partial esters

Bisphosphonate prodrugs: synthesis and vitro evaluation of alkyl and acyloxymethyl esters of etidronic acid as bioreversible prodrugs of etidronate