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Petri Turhanen

Petri Turhanen

Staff Scientist

School of Pharmacy, Faculty of Health Sciences

[email protected] | +358 40 355 3857

Information Publications

Research groups

Transporter-Targeted Drug Delivery 01.09.2012 -
Medicinal chemistry and organic synthesis facilities 01.01.2010 -
Applied chemistry 01.01.2012 -

Publications

61/61 items

Green phosphonate chemistry - Does it exist?
Demadis, Konstantinos D; Adla, Santosh Kumar; Timonen, Juri; Turhanen, Petri A, 2024, Green chemistry, 2025; 27, 4, 863-914. A2 Review article, Literature review, Systematic review
TRPA1 Inhibition Effects by 3-Phenylcoumarin Derivatives
Sallomy, Carita; Awolade, Paul; Rahnasto-Rilla, Minna; Hämäläinen, Mari; Nousiainen, Liisa P; Johansson, Niklas G; Hiltunen, Sanna; Turhanen, Petri; Moilanen, Eeva; Lahtela-Kakkonen, Maija; Timonen, Juri M, 2024, Acs medicinal chemistry letters, 15, 8, 1221-1226. A1 Journal article (refereed), original research
Simple and User-Friendly Methodology for Crystal Water Determination by Quantitative Proton NMR Spectroscopy in Deuterium Oxide
Tynkkynen, Tuulia; Vassaki, Maria; Tiihonen, Tommi E.; Lehto, Vesa-Pekka; Demadis, Konstantinos D.; Turhanen, Petri A., 2023, Analytical chemistry, 95, 46, 17020-17027. A1 Journal article (refereed), original research
Structural Diversity in Antiosteolytic Bisphosphonates: Deciphering Structure–Activity Trends in Ultra Long Controlled Release Phenomena
Vassaki, Maria; Hadjicharalambous, Chrystalleni; Turhanen, Petri A.; Demadis, Konstantinos D., 2023, ACS applied bio materials, 6, 12, 5563-5581. A1 Journal article (refereed), original research
Surface-Modified Silica Hydrogels for the Programmable Release of Bisphosphonate Anti-Osteoporosis Drugs: The Case of Etidronate
Alatzoglou, Fanouria-Eirini G; Vassaki, Maria; Nirgianaki, Kalliopi; Tripodianos, Eleftherios; Turhanen, Petri; Demadis, Konstantinos D; Papathanasiou, Konstantinos E, 2023, Materials, 16, 9, 3379. A1 Journal article (refereed), original research
3-(3-Bromophenyl)-7-acetoxycoumarin
Turhanen, Petri A; Nousiainen, Liisa P; Timonen, Juri M, 2022, Molbank, 2022, 4, M1513. A1 Journal article (refereed), original research
6-Bromo-1-hydroxyhexane-1,1-bisphosphonic Acid Monosodium Salt
Turhanen, Petri A, 2022, Molbank, 2022, 4, M1476. A1 Journal article (refereed), original research
Drug-Inclusive Inorganic–Organic Hybrid Systems for the Controlled Release of the Osteoporosis Drug Zoledronate
Vassaki, Maria; Lazarou, Savvina; Turhanen, Petri; Choquesillo-Lazarte, Duane; Demadis, Konstantinos D, 2022, Molecules, 27, 19, 6212. A1 Journal article (refereed), original research
Editorial: Phosphonate chemistry in drug design and development, Volume II
Turhanen, Petri A; Kafarski, Pawel, 2022, Frontiers in chemistry, 10, 1054145. B1 Non-refereed journal articles
Functionalized nanoporous silicon for extraction of Sc from a leach solution
Rahmani, Arezoo; Thapa, Rinez; Aalto, Juha Matti; Turhanen, Petri; Vepsäläinen, Jouko; Lehto, Vesa Pekka; Riikonen, Joakim, 2022, Hydrometallurgy, 211, 105866. A1 Journal article (refereed), original research
Importance of Organophosphorus Compounds in Medicinal Chemistry Field
Turhanen, Petri A, 2022, Journal of biomedical research & environmental sciences, 3, 2, 195-197. A1 Journal article (refereed), original research
Real-Time On-Site Multielement Analysis of Environmental Waters with a Portable X-ray Fluorescence (pXRF) System
Tiihonen, Tommi E; Nissinen, Tuomo J; Turhanen, Petri A; Vepsäläinen, Jouko J; Riikonen, Joakim; Lehto, Vesa Pekka, 2022, Analytical chemistry, 94, 34, 11739-11744. A1 Journal article (refereed), original research
Synthesis and Theoretical Studies of Aromatic Azaborines
Hirva, Pipsa; Turhanen, Petri; Timonen, Juri M, 2022, Organics, 3, 3, 196-209. A1 Journal article (refereed), original research
Synthesis of the biologically important dideuterium-labelled adenosine triphosphate analogue ApppI(d2)
Turhanen, Petri A, 2022, Beilstein journal of organic chemistry, 18, 1466-1470. A1 Journal article (refereed), original research
Calcium and Strontium Coordination Polymers as Controlled Delivery Systems of the Anti-Osteoporosis Drug Risedronate and the Augmenting Effect of Solubilizers
Vassaki, Maria; Kotoula, Christina; Turhanen, Petri; Choquesillo-Lazarte, Duane; Demadis, Konstantinos D., 2021, Applied sciences, 11, 23, 11383. A1 Journal article (refereed), original research
Editorial: Phosphonate Chemistry in Drug Design and Development
Turhanen, Petri A; Demadis, Konstantinos D; Kafarski, Pawel, 2021, Frontiers in chemistry, 9, 695128. B1 Non-refereed journal articles
Meyer-Schuster Rearrangement - Convenient Synthesis of α,ß-Unsaturated α-Iodinated Aldehydes and Ketones
Timonen, Juri M; Turhanen, Petri A, 2021, General chemistry, 7, 2, 200023. A1 Journal article (refereed), original research
Plant-based nanostructured silicon carbide modified with bisphosphonates for metal adsorption
Haluska, Ondrej; Rahmani, Arezoo; Salami, Ayobami; Turhanen, Petri; Vepsäläinen, Jouko; Lappalainen, Reijo; Lehto, Vesa-Pekka; Riikonen, Joakim, 2021, Microporous and mesoporous materials, 324, 111294. A1 Journal article (refereed), original research
Recovery of uranium with bisphosphonate modified mesoporous silicon
Thapa, Rinez; Rahmani, Arezoo; Turhanen, Petri; Taskinen, Antti; Nissinen, Tuomo; Neitola, Raisa; Vepsäläinen, Jouko; Lehto, Vesa-Pekka; Riikonen, Joakim, 2021, Separation and purification technology, 272, 118913. A1 Journal article (refereed), original research
Rapid synthesis of nanostructured porous silicon carbide from biogenic silica
Riikonen, Joakim; Rantanen, Jimi; Thapa, Rinez; Le, Nguyen T; Rigolet, Severinne; Fioux, Philippe; Turhanen, Petri; Bodiford, Nelli K; Kalluri, Jhansi R; lkonen, Timo; Nissinen, Tuomo; Lebeau, Benedicte; Vepsäläinen, Jouko; Coffer, Jeffery L; Lehto, Vesa-Pekka, 2020, Journal of the American Ceramic Society, 2021; 104, 2, 766-775. A1 Journal article (refereed), original research
Self-sacrificial MOFs for ultra-long controlled release of bisphosphonate anti-osteoporotic drugs
Vassaki, Maria; Papathanasiou, Konstantinos; Hadjicharalambous, Chrystalleni; Chandrinou, Daphne; Turhanen, Petri; Choquesillo-Lazarte, Duane; Demadis, Konstantinos, 2020, Chemical communications, 56, 38, 5166-5169. A1 Journal article (refereed), original research
The serendipitous discovery of a new green chemistry method
Turhanen, Petri, 2020, Research outreach, 112, 6-9. B1 Non-refereed journal articles
(E)-Di-iodination of Alkynes Using Dried Dowex H+/NaI Approach
Timonen, Juri M; Turhanen, Petri A, 2019, ACS omega, 4, 11, 14663-14668. A1 Journal article (refereed), original research
Bisphosphonate modified mesoporous silicon for scandium adsorption
Thapa, Rinez; Nissinen, Tuomo; Turhanen, Petri; Määttä, Juha; Vepsäläinen, Jouko; Lehto, Vesa-Pekka; Riikonen, Joakim, 2019, Microporous and mesoporous materials, 2020; 296, 109980. A1 Journal article (refereed), original research
Green and Efficient Esterification Method Using Dried Dowex H+/NaI Approach
Turhanen, Petri; Leppänen, Jukka; Vepsäläinen, Jouko J, 2019, ACS omega, 4, 5, 8974-8984. A1 Journal article (refereed), original research
Bisphosphonate-Generated ATP-Analogs Inhibit Cell Signaling Pathways
Malwal, SR; O'Dowd, B; Feng, X; Turhanen, PA; Shin, CJ; Yao, J; Kim, BK; Baig, N; Zhou, T; Bansal, S; Khade, R;, Zhang, Y; Oldfield, E, 2018, Journal of the American Chemical Society, 140, 24, 7568-7578. A1 Journal article (refereed), original research
Integrated analysis of isopentenyl pyrophosphate (IPP) toxicity in isoprenoid-producing Escherichia coli
George, KW; Thompson, M; Kim, J; Baidoo, EEK; Wang, G; Benites, VT; Petzold, CJ; Chan, LJG; Yilmaz, S; Turhanen, P; Adams, PD; Keasling, JD; Lee, TS, 2018, Metabolic engineering, 47, 60-72. A1 Journal article (refereed), original research
Phosphorus chemistry: from small molecules, to polymers, to pharmaceutical and industrial applications
Papathanasiou, Konstantinos E; Vassaki, Maria; Spinthaki, Argyro; Alatzoglou, Fanouria-Eirini G; Tripodianos, Eleftherios; Turhanen, Petri; Demadis, Konstantinos D, 2018, Pure and applied chemistry, 2019; 91, 3, 421-4411-21. A1 Journal article (refereed), original research
Selective Calcium-Dependent Inhibition of ATP-Gated P2X3 Receptors by Bisphosphonate-Induced Endogenous ATP Analog ApppI
Ishchenko Y, Shakirzyanova A, Giniatullina R, Skorinkin A, Bart G, Turhanen P, Määttä JA, Mönkkönen J, Giniatullin R, 2017, Journal of pharmacology and experimental therapeutics, 361, 3, 472-481. A1 Journal article (refereed), original research
Semi-preparative high-performance countercurrent chromatography method for the purification of chemically synthesized ATP analogue, ApppI.
Puljula E, Turhanen PA, 2017, Journal of chromatography b: analytical technologies in the biomedical and life sciences, 1063, 180-182. A1 Journal article (refereed), original research
Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs
Papathanasiou Konstantinos E, Turhanen Petri, Brueckner Stephan I, Brunner Eike, Demadis Konstantinos D, 2017, Scientific reports, 7, 4743. A1 Journal article (refereed), original research
Synthesis of a Biologically Important Adenosine Triphosphate Analogue, ApppD
Turhanen Petri, 2017, ACS omega, 2, 6, 2835-2838. A1 Journal article (refereed), original research
Preparation of useful building blocks, a-iodo- and bromoalkanols from cyclic ethers using the Dowex H+/NaX (X = I, Br) approach
Turhanen Petri, Vepsäläinen Jouko, 2016, Rsc advances, 6, 15937-15940. A1 Journal article (refereed), original research
Synthesis of medronic acid monoesters and their purification by high-performance countercurrent chromatography or by hydroxyapatite
Puljula Elina, Vepsäläinen Jouko, Turhanen Petri, 2016, Beilstein journal of organic chemistry, 12, 2145-2149. A1 Journal article (refereed), original research
A powerful tool for acid catalyzed organic addition and substitution reactions
Turhanen Petri, Vepsäläinen Jouko, 2015, Rsc advances, 5, 26218-26222. A1 Journal article (refereed), original research
Advanced material and approach for metal ions removal from aqueous solutions
Turhanen Petri A, Vepsäläinen Jouko J, Peräniemi Sirpa, 2015, Scientific reports, 5, 8992. A1 Journal article (refereed), original research
Selective acetylation of primary amino groups with phenyl acetate: simple conversion of polyamines into N,N'-diacetyl derivatives
Ucal Sebahat, Khomutov Alex R, Häkkinen Merja R, Turhanen Petri A, Vepsäläinen Jouko J, Weisell Janne, 2015, Arkivoc, 2015, 7, 42-49. A1 Journal article (refereed), original research
Structural Requirements for Bisphosphonate Binding on Hydroxyapatite: NMR Study of Bisphosphonate Partial Esters
Puljula Elina, Turhanen Petri, Vepsäläinen Jouko, Monteil Maelle, Lecouvey Marc, Weisell Janne, 2015, Acs medicinal chemistry letters, 6, 4, 397-401. A1 Journal article (refereed), original research
Two strategies for the synthesis of the biologically important ATP analogue ApppI, at a multi-milligram scale
Weisell Janne, Vepsäläinen Jouko, Turhanen Petri A, 2015, Beilstein journal of organic chemistry, 11, 2189-2193. A1 Journal article (refereed), original research
Synthesis of Triple-Bond-Containing 1-Hydroxy-1,1-bisphosphonic Acid Derivatives To Be Used as Precursors in "Click" Chemistry: Two Examples
Turhanen Petri A, 2014, Journal of organic chemistry, 79, 6330-6335. A1 Journal article (refereed), original research
A bisphosphonate increasing the shoot biomass of the metal hyperaccumulator Noccaea caerulescens
Alanne Aino-Liisa, Peräniemi Sirpa, Turhanen Petri, Tuomainen Marjo, Vepsäläinen Jouko, Tervahauta Arja, 2013, Chemosphere, 2014:95, 566-571. A1 Journal article (refereed), original research
A novel bisphosphonate-based solid phase method for effective removal of chromium(III) from aqueous solutions and tannery effluents
Alanne Aino-Liisa, Tuikka Matti, Tõnsuaadu Kaia, Ylisirniö Markku, Hämäläinen Lea, Turhanen Petri, Vepsäläinen Jouko, Peräniemi Sirpa, 2013, Rsc advances, 3, 14132-14138. A1 Journal article (refereed), original research
Firefly luciferase inhibitor-conjugated peptide quenches bioluminescence: a versatile tool for real time monitoring cellular uptake of biomolecules
Poutiainen Pekka K, Rönkkö Teemu, Hinkkanen Ari E, Palvimo Jorma J, Närvänen Ale, Turhanen Petri, Laatikainen Reino, Weisell Janne, Pulkkinen Juha T, 2013, Bioconjugate chemistry, 2014:25, 4-10. A1 Journal article (refereed), original research
First bisphosphonate hydrogelators: potential composers of biocompatible gels
Alanne Aino-Liisa, Lahtinen Manu, Löfman Miika, Turhanen Petri, Kolehmainen Erkki, Vepsäläinen Jouko, Sievänen Elina, 2013, Journal of materials chemistry. b, 1, 6201-6212. A1 Journal article (refereed), original research
The selective stepwise chemical hydrolysis of alkylcarbonate groups from novel mixed alkylcarbonate trialkyl ester derivatives of etidronic acid
Turhanen Petri A, Weisell Janne, Vepsäläinen Jouko J, 2013, Rsc advances, 3, 2417-2421. A1 Journal article (refereed), original research
Large glucosylthioureidocalixarenes: selective hosts for mono- and bisphosphonates
Torvinen Mika, Kalenius Elina, Sansone Francesco, Casnati Alessandro, Turhanen Petri, Jänis Janne, 2012, Supramolecular chemistry, 24, 4, 228-233. A1 Journal article (refereed), original research
Preparation of mixed trialkyl alkylcarbonate derivates of etidronic acid via an unusual route
Turhanen Petri A, Weisell Janne, Vepsäläinen Jouko J, 2012, Beilstein journal of organic chemistry, 8, 2019-2024. A1 Journal article (refereed), original research
Systematic study of the physicochemical properties of a homologous series of aminobisphosphonates
Alanne Aino-Liisa, Hyvönen Helena, Lahtinen Manu, Ylisirniö Markku, Turhanen Petri, Kolehmainen Erkki, Peräniemi Sirpa, Vepsäläinen Jouko, 2012, Molecules, 17, 9, 10928-10945. A1 Journal article (refereed), original research
A novel strategy for the synthesis of enzymatically stable biotin-DOTA conjugates for in vivo use
Turhanen Petri A, Weisell Janne, Lehtolainen-Dalkilic Pauliina, Määttä Ann-Marie, Vepsäläinen Jouko, Närvänen Ale, 2011, Medchemcomm, 2, 2, 886-888. A1 Journal article (refereed), original research
Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions
Turhanen PA, Vepsäläinen JJ, 2008, Beilstein journal of organic chemistry, 4, 7. A1 Journal article (refereed), original research
A novel strategy for the preparation of naturally occurring phosphocitrate and its partially esterfied derivatives
Turhanen PA, Demadis KD, Peräniemi S, Vepsäläinen JJ, 2007, Journal of organic chemistry, 72, 4, 1468-1471. A1 Journal article (refereed), original research
Synthesis of novel (1-alkanoyloxy-4-alkanoylaminobutylidene)-1,1-bisphosphonic acid derivatives
Turhanen P, Vepsalainen JJ, 2006, Beilstein journal of organic chemistry, 2:2. A1 Journal article (refereed), original research
Synthesis of novel fatty acid derivatives of etidronic acid
Turhanen PA, Vepsäläinen JJ, 2005, Synthesis: stuttgart, 18, 3063-3066. A1 Journal article (refereed), original research
The first synthesis of novel (1-alkoxycarbonyloxyethylidene)-1,1-bisphosphonic acid derivatives taking advantage of the rearrangement characteristic of the tetramethyl ester of etidronate
Turhanen PA, Vepsäläinen JJ, 2005, Synthesis: stuttgart, 13, 2119-2121. A1 Journal article (refereed), original research
One-pot synthesis of 1-[(1-phenyl-1-dialkoxyphosphoryl)-methyl]-2-pyrrolidinone
Turhanen PA, Soininen P, Vepsäläinen JJ, 2004, Letters in organic chemistry, 1, 343-345. A1 Journal article (refereed), original research
Strategies for the preparation of (1-acetyloxyethylidene)-1,1-bisphosphonic acid derivatives
Turhanen PA, Vepsäläinen JJ, 2004, Synthesis: stuttgart, 7, 0992-0994. A1 Journal article (refereed), original research
Design and Synthesis of Novel (I-Hydroxyethylidene)-I, I-Bisphosphonic Acid Derivatives as Possible Prodrugs of Etidronate
Turhanen P, 2003, Kuopion yliopiston julkaisuja C. Luonnontieteet ja ympäristötieteet. G5 Doctoral dissertation (article)
First synthesis of etidronate partial amides starting from PCI3
Turhanen PA, Niemi R, Peräkylä M, Järvinen T, Vepsäläinen JJ, 2003, Organic and biomolecular chemistry, 1, 3223-3226. A1 Journal article (refereed), original research
Bisphosphonate prodrugs. Synthesis and identification of (1-hydroxyethylidene)-1,1-bisphosphonic acid tetraesters by mass spectrometry, NMR spectroscopy and X-ray crystallography
Turhanen PA, Ahlgren MJ, Järvinen T, Vepsäläinen JJ, 2001, PHOSPHORUS, SULFUR, AND SILICON AND THE RELATED ELEMENTS, 170, 115-133. A1 Journal article (refereed), original research
Bisphosphonate prodrugs: selective synthesis of (1-hydroxyethylidene)-1,1-bisphosphonate partial esters
Turhanen PA, Ahlgren MJ, Järvinen T, Vepsäläinen J, 2001, Synthesis: stuttgart, 4, 633-637. A1 Journal article (refereed), original research
Bisphosphonate prodrugs: synthesis and vitro evaluation of alkyl and acyloxymethyl esters of etidronic acid as bioreversible prodrugs of etidronate
Niemi R, Turhanen P, Vepsäläinen J, Taipale H, Järvinen T, 2000, European journal of pharmaceutical sciences, 11, 173-180. A1 Journal article (refereed), original research

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Petri Turhanen

Research groups

Green phosphonate chemistry - Does it exist?

TRPA1 Inhibition Effects by 3-Phenylcoumarin Derivatives

Simple and User-Friendly Methodology for Crystal Water Determination by Quantitative Proton NMR Spectroscopy in Deuterium Oxide

Structural Diversity in Antiosteolytic Bisphosphonates: Deciphering Structure–Activity Trends in Ultra Long Controlled Release Phenomena

Surface-Modified Silica Hydrogels for the Programmable Release of Bisphosphonate Anti-Osteoporosis Drugs: The Case of Etidronate

3-(3-Bromophenyl)-7-acetoxycoumarin

6-Bromo-1-hydroxyhexane-1,1-bisphosphonic Acid Monosodium Salt

Drug-Inclusive Inorganic–Organic Hybrid Systems for the Controlled Release of the Osteoporosis Drug Zoledronate

Editorial: Phosphonate chemistry in drug design and development, Volume II

Functionalized nanoporous silicon for extraction of Sc from a leach solution

Importance of Organophosphorus Compounds in Medicinal Chemistry Field

Real-Time On-Site Multielement Analysis of Environmental Waters with a Portable X-ray Fluorescence (pXRF) System

Synthesis and Theoretical Studies of Aromatic Azaborines

Synthesis of the biologically important dideuterium-labelled adenosine triphosphate analogue ApppI(d2)

Calcium and Strontium Coordination Polymers as Controlled Delivery Systems of the Anti-Osteoporosis Drug Risedronate and the Augmenting Effect of Solubilizers

Editorial: Phosphonate Chemistry in Drug Design and Development

Meyer-Schuster Rearrangement - Convenient Synthesis of α,ß-Unsaturated α-Iodinated Aldehydes and Ketones

Plant-based nanostructured silicon carbide modified with bisphosphonates for metal adsorption

Recovery of uranium with bisphosphonate modified mesoporous silicon

Rapid synthesis of nanostructured porous silicon carbide from biogenic silica

Self-sacrificial MOFs for ultra-long controlled release of bisphosphonate anti-osteoporotic drugs

The serendipitous discovery of a new green chemistry method

(E)-Di-iodination of Alkynes Using Dried Dowex H+/NaI Approach

Bisphosphonate modified mesoporous silicon for scandium adsorption

Green and Efficient Esterification Method Using Dried Dowex H+/NaI Approach

Bisphosphonate-Generated ATP-Analogs Inhibit Cell Signaling Pathways

Integrated analysis of isopentenyl pyrophosphate (IPP) toxicity in isoprenoid-producing Escherichia coli

Phosphorus chemistry: from small molecules, to polymers, to pharmaceutical and industrial applications

Selective Calcium-Dependent Inhibition of ATP-Gated P2X3 Receptors by Bisphosphonate-Induced Endogenous ATP Analog ApppI

Semi-preparative high-performance countercurrent chromatography method for the purification of chemically synthesized ATP analogue, ApppI.

Smart, programmable and responsive injectable hydrogels for controlled release of cargo osteoporosis drugs

Synthesis of a Biologically Important Adenosine Triphosphate Analogue, ApppD

Preparation of useful building blocks, a-iodo- and bromoalkanols from cyclic ethers using the Dowex H+/NaX (X = I, Br) approach

Synthesis of medronic acid monoesters and their purification by high-performance countercurrent chromatography or by hydroxyapatite

A powerful tool for acid catalyzed organic addition and substitution reactions

Advanced material and approach for metal ions removal from aqueous solutions

Selective acetylation of primary amino groups with phenyl acetate: simple conversion of polyamines into N,N'-diacetyl derivatives

Structural Requirements for Bisphosphonate Binding on Hydroxyapatite: NMR Study of Bisphosphonate Partial Esters

Two strategies for the synthesis of the biologically important ATP analogue ApppI, at a multi-milligram scale

Synthesis of Triple-Bond-Containing 1-Hydroxy-1,1-bisphosphonic Acid Derivatives To Be Used as Precursors in "Click" Chemistry: Two Examples

A bisphosphonate increasing the shoot biomass of the metal hyperaccumulator Noccaea caerulescens

A novel bisphosphonate-based solid phase method for effective removal of chromium(III) from aqueous solutions and tannery effluents

Firefly luciferase inhibitor-conjugated peptide quenches bioluminescence: a versatile tool for real time monitoring cellular uptake of biomolecules

First bisphosphonate hydrogelators: potential composers of biocompatible gels

The selective stepwise chemical hydrolysis of alkylcarbonate groups from novel mixed alkylcarbonate trialkyl ester derivatives of etidronic acid

Large glucosylthioureidocalixarenes: selective hosts for mono- and bisphosphonates

Preparation of mixed trialkyl alkylcarbonate derivates of etidronic acid via an unusual route

Systematic study of the physicochemical properties of a homologous series of aminobisphosphonates

A novel strategy for the synthesis of enzymatically stable biotin-DOTA conjugates for in vivo use

Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions

A novel strategy for the preparation of naturally occurring phosphocitrate and its partially esterfied derivatives

Synthesis of novel (1-alkanoyloxy-4-alkanoylaminobutylidene)-1,1-bisphosphonic acid derivatives

Synthesis of novel fatty acid derivatives of etidronic acid

The first synthesis of novel (1-alkoxycarbonyloxyethylidene)-1,1-bisphosphonic acid derivatives taking advantage of the rearrangement characteristic of the tetramethyl ester of etidronate

One-pot synthesis of 1-[(1-phenyl-1-dialkoxyphosphoryl)-methyl]-2-pyrrolidinone

Strategies for the preparation of (1-acetyloxyethylidene)-1,1-bisphosphonic acid derivatives

Design and Synthesis of Novel (I-Hydroxyethylidene)-I, I-Bisphosphonic Acid Derivatives as Possible Prodrugs of Etidronate

First synthesis of etidronate partial amides starting from PCI3

Bisphosphonate prodrugs. Synthesis and identification of (1-hydroxyethylidene)-1,1-bisphosphonic acid tetraesters by mass spectrometry, NMR spectroscopy and X-ray crystallography

Bisphosphonate prodrugs: selective synthesis of (1-hydroxyethylidene)-1,1-bisphosphonate partial esters

Bisphosphonate prodrugs: synthesis and vitro evaluation of alkyl and acyloxymethyl esters of etidronic acid as bioreversible prodrugs of etidronate