SUVI JAUHIAINEN

Contact info

Research groups - UEF

• 
  Molecular Medicine
• 
  Vascular Biology (Laakkonen)

Publications

• Jauhiainen, Suvi; Laakkonen, Johanna P; Ketola, Kirsi; Toivanen, Pyry, I; Nieminen, Tina; Ninchoji, Takeshi; Levonen, Anna-Liisa; Kaikkonen, Minna U; Ylä-Herttuala, Seppo. 2019. Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function Frontiers in physiology 10: 224. 2019
• Laakkonen, Johanna P; Lähteenvuo, Johanna; Jauhiainen, Suvi; Heikura, Tommi; Ylä-Herttuala, Seppo. 2019. Beyond endothelial cells: Vascular endothelial growth factors in heart, vascular anomalies and placenta Vascular pharmacology 112: 91-101. 2019
• Nikolaev, Sergey I; Vetiska, Sandra; Bonilla, Ximena; Boudreau, Emilie; Jauhiainen, Suvi; Jahromi, Behnam Rezai; Khyzha, Nadiya; DiStefano, Peter V; Suutarinen, Santeri; Kiehl, Tim-Rasmus; Pereira, Vitor Mendes; Herman, Alexander M; Krings, Timo; Andrade-Barazarte, Hugo; Tung, Takyee; Valiante, Taufik; Zadeh, Gelareh; Tymianski, Mike; Rauramaa, Tuomas; Ylä-Herttuala, Seppo; et al.. 2018. Verisuonten seinämien somaattiset mutaatiot aivojen valtimo-laskimoepämuodostumien aiheuttajina Duodecim 134 3: 298. 2018
• Nikolaev, SI; Vetiska, S; Bonilla, X; Boudreau, E; Jauhiainen, S; Rezai, Jahromi B; Khyzha, N; DiStefano, PV; Suutarinen, S; Kiehl, TR; Mendes Pereira, V; Herman, AM; Krings, T; Andrade-Barazarte, H; Tung, T; Valiante, T; Zadeh, G; Tymianski, M; Rauramaa, T; Ylä-Herttuala, S et al.. 2018. Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain. NEW ENGLAND JOURNAL OF MEDICINE 378 3: 250-261. 2018
• Laakkonen Johanna P, Lappalainen Jari P, Theelen Thomas L, Toivanen Pyry I, Nieminen Tiina, Jauhiainen Suvi,Kaikkonen Minna U, Sluimer Judith C, Ylä-Herttuala Seppo. 2016. Differential regulation of angiogenic cellular processes and claudin-5 by histamine and VEGF via PI3K-signaling, transcription factor SNAI2 and interleukin-8. Angiogenesis [Epub ahead of print 21 Nov 2016]: 1-16. 2016
• Jauhiainen Suvi. 2015. Vascular endothelial growth factors and their receptors in endothelial cells and in pathological conditions. Itä-Suomen yliopisto. Publications of the University of Eastern Finland. Dissertations in Health Sciences 272. 2015
• Nieminen T, Toivanen PI, Rintanen N, Heikura T, Jauhiainen S, Airenne KJ, Alitalo K, Marjomäki V, Ylä-Herttuala S. 2013. The impact of the receptor binding profiles of the vascular endothelial growth factors on their angiogenic features. BIOCHIMICA ET BIOPHYSICA ACTA 1840 1: 454-463. 2013
• Ylä-Herttuala S, Bentzon JF, Daemen M, Falk E, Garcia-Garcia HM, Herrmann J, Hoefer I, Jauhiainen S, Jukema JW, Krams R, Kwak BR, Marx N, Naruszewicz M, Newby A, Pasterkamp G, Serruys PW, Waltenberger J, Weber C, Tokgözoglu L; ESC Working Group of Atherosclerosis and Vascular Biology. 2013. Stabilization of atherosclerotic plaques: an update. EUROPEAN HEART JOURNAL 34 42: 3251-8. 2013
• Vuorio, T., Jauhiainen, S., Ylä-Herttuala, S. 2012. Pro- and anti-angiogenic therapy and atherosclerosis with special emphasis on vascular endothelial growth factors. EXPERT OPINION ON BIOLOGICAL THERAPY 2012 Jan;12(1): 79-92. 2012
• Partanen TA, Vuola P, Jauhiainen S, Lohi J, Salminen P, Pitkäranta A, Häkkinen SK, Honkonen K, Alitalo K, Ylä-Herttuala S. 2012. Neuropilin-2 and vascular endothelial growth factor receptor-3 are up-regulated in human vascular malformations. Angiogenesis 2012 Sep 9. [Epub ahead of print]: --. 2012
• Kivelä AM, Dijkstra MH, Heinonen SE, Gurzeler E, Jauhiainen S, Levonen AL, Ylä-Herttuala S. 2012. Regulation of endothelial lipase and systemic HDL cholesterol levels by SREBPs and VEGF-A. ATHEROSCLEROSIS 2012 Oct 9. [Epub ahead of print] pii: S0021-9150(12)00657-0.: --. 2012
• Jauhiainen Suvi, Häkkinen Sanna-Kaisa, Toivanen Pyry I, Heinonen Suvi E, Jyrkkänen Henna-Kaisa, Kansanen Emilia, Leinonen Hanna, Levonen Anna-Liisa, Ylä-Herttuala Seppo. 2011. Vascular endothelial growth factor (VEGF)-D stimulates VEGF-A, stanniocalcin-1, and neuropilin-2 and has potent angiogenic effects. ARTERIOSCLEROSIS, THROMBOSIS AND VASCULAR BIOLOGY 31: 1617-1624. 2011
• Toivanen PI, Nieminen T, Viitanen L, Alitalo A, Roschier M, Jauhiainen S, Markkanen JE, Laitinen OH, Airenne TT, Salminen TA, Johnson MS, Airenne KJ, Ylä-Herttuala S. 2009. Novel vascular endothelial growth factor D variants with increased biological activity. JOURNAL OF BIOLOGICAL CHEMISTRY 284 23: 16037-16048. 2009
• Jyrkkänen H-K, Kansanen E, Inkala M, Kivelä AM, Hurttila H, Heinonen SE, Goldsteins G, Jauhiainen S, Tiainen S, Makkonen H, Oskolkova O, Afonyushkin T, Koistinaho J, Yamamoto M, Bochkov VN, Ylä-Herttuala S, Levonen A-L. 2008. Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo CIRCULATION RESEARCH [ONLINE: HTTP://CIRCRES.AHAJOURNALS.ORG/] 103: e1-e9. 2008
• Levonen A-L, Inkala M, Heikura T, Jauhiainen S, Jyrkkänen H-K, Kansanen E, Määttä K, Romppanen E, Turunen P, Rutanen J, Ylä-Herttuala S. 2007. Nrf2 gene transfer induces antioxidant enzymes and suppresses smooth muscle cell growth in vitro and reduces oxidative stress in rabbit aorta in vivo. ARTERIOSCLEROSIS, THROMBOSIS AND VASCULAR BIOLOGY 27: 741-747. 2007
• Bhardwaj S, Roy H, Kärpänen T, Hi Y, Jauhiainen S, Hedman M, Alitalo K, Ylä-Herttuala S. 2005. Periadventitial angiopoietin-1 gene transfer induces angiogenesis in rabbit carotid arteries. GENE THERAPY 12 5: 388-394. 2005
• Roy H, Bhardwaj S, Babu M, Jauhiainen S, Herzig K-H, Bellu AR, Haisma HJ, Carmeliet P, Alitalo K, Ylä-Herttuala S. 2005. Adenovirus-mediated gene transfer of placental growth factor to perivascular tissue induces angiogenesis via upregulation of the expression of endogenous vascular endothelial growth factor-A. HUMAN GENE THERAPY 16 12: 1422-1428. 2005
• Rutanen J, Turunen A-M, Teittinen M, Rissanen TT, Heikura T, Koponen JK, Gruchala M, Inkala M, Jauhiainen S, Hiltunen MO, Turunen MP, Stacker SA, Achen MG, Ylä-Herttuala S. 2005. Gene transfer using the mature form of VEGF-D reduces neointimal thickening through nitric oxide-dependent mechanism. GENE THERAPY 12: 980-987. 2005
• Rissanen TT, Markkanen JE, Arve K, Rutanen J, Kettunen MI, Vajanto I, Jauhiainen S, Cashion L, Gruchala M, Närvänen O, Taipale P, Kauppinen RA, Rubanyi GM, Ylä-Herttuala S. 2003. Fibroblast growth factor-4 induces vascular permeability, angiogenesis, and arteriogenesis in a rabbit hind limb ischemia model. FASEB JOURNAL 17: 100-102. 2003