Suvi Jauhiainen

Proteomics on human cerebral cavernous malformations reveals novel biomarkers in neurovascular dysfunction for the disease pathology

Jauhiainen, Suvi; Onyeogaziri, Favour C; Lazzaroni, Francesca; Conze, Lei Liu; Laakkonen, Johanna P.; Karam, Nihay Laham; Laakso, Aki; Niemelä, Mika; Jahromi, Behnam Rezai; Magnusson, Peetra U.. 2024. Biochimica et biophysica acta: molecular basis of disease. 1870: A1 Journal article (refereed), original research

ErbB signalling is a potential therapeutic target for vascular lesions with fibrous component

Jauhiainen, Suvi; Ilmonen, Henna; Vuola, Pia; Rasinkangas, Heta; Pulkkinen, Heidi H; Keränen, Sara; Kiema, Miika; Liikkanen, Jade J; Laham Karam, Nihay; Laidinen, Svetlana; Beter, Mustafa; Aavik, Einari; Lappalainen, Kimmo; Lohi, Jouko; Aronniemi, Johanna; Örd, Tiit; Kaikkonen, Minna U; Salminen, Päivi; Tukiainen, Erkki; Ylä-Herttuala, Seppo; Laakkonen, Johanna P. 2023. eLife. 12: A1 Journal article (refereed), original research

Large Vessel Cell Heterogeneity and Plasticity: Focus in Aortic Aneurysms

Jauhiainen, Suvi; Kiema, Miika; Hedman, Marja; Laakkonen, Johanna P. 2022. Arteriosclerosis, thrombosis, and vascular biology. 42: 811-818 A2 Review article, Literature review, Systematic review

Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function

Jauhiainen, Suvi; Laakkonen, Johanna P; Ketola, Kirsi; Toivanen, Pyry, I; Nieminen, Tina; Ninchoji, Takeshi; Levonen, Anna-Liisa; Kaikkonen, Minna U; Ylä-Herttuala, Seppo. 2019. Frontiers in physiology. 10: 224 A1 Journal article (refereed), original research

Beyond endothelial cells: Vascular endothelial growth factors in heart, vascular anomalies and placenta

Laakkonen, Johanna P; Lähteenvuo, Johanna; Jauhiainen, Suvi; Heikura, Tommi; Ylä-Herttuala, Seppo. 2019. Vascular pharmacology. 112: 91-101 A2 Review article, Literature review, Systematic review

Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain

Nikolaev, SI; Vetiska, S; Bonilla, X; Boudreau, E; Jauhiainen, S; Rezai, Jahromi B; Khyzha, N; DiStefano, PV; Suutarinen, S; Kiehl, TR; Mendes Pereira, V; Herman, AM; Krings, T; Andrade-Barazarte, H; Tung, T; Valiante, T; Zadeh, G; Tymianski, M; Rauramaa, T; Ylä-Herttuala, S et al.. 2018. The new england journal of medicine. 378: 250-261 A1 Journal article (refereed), original research

Verisuonten seinämien somaattiset mutaatiot aivojen valtimo-laskimoepämuodostumien aiheuttajina

Nikolaev, Sergey I; Vetiska, Sandra; Bonilla, Ximena; Boudreau, Emilie; Jauhiainen, Suvi; Jahromi, Behnam Rezai; Khyzha, Nadiya; DiStefano, Peter V; Suutarinen, Santeri; Kiehl, Tim-Rasmus; Pereira, Vitor Mendes; Herman, Alexander M; Krings, Timo; Andrade-Barazarte, Hugo; Tung, Takyee; Valiante, Taufik; Zadeh, Gelareh; Tymianski, Mike; Rauramaa, Tuomas; Ylä-Herttuala, Seppo; et al.. 2018. Duodecim. 134: 298 D1 Article in a trade journal

Differential regulation of angiogenic cellular processes and claudin-5 by histamine and VEGF via PI3K-signaling, transcription factor SNAI2 and interleukin-8

Laakkonen Johanna P, Lappalainen Jari P, Theelen Thomas L, Toivanen Pyry I, Nieminen Tiina, Jauhiainen Suvi,Kaikkonen Minna U, Sluimer Judith C, Ylä-Herttuala Seppo. 2016. Angiogenesis. [Epub ahead of print 21 Nov 2016]: 1-16 A1 Journal article (refereed), original research

Vascular endothelial growth factors and their receptors in endothelial cells and in pathological conditions

Jauhiainen Suvi. 2015. Publications of the University of Eastern Finland. Dissertations in Health Sciences G5 Doctoral dissertation (article)

Stabilization of atherosclerotic plaques: an update

Ylä-Herttuala S, Bentzon JF, Daemen M, Falk E, Garcia-Garcia HM, Herrmann J, Hoefer I, Jauhiainen S, Jukema JW, Krams R, Kwak BR, Marx N, Naruszewicz M, Newby A, Pasterkamp G, Serruys PW, Waltenberger J, Weber C, Tokgözoglu L; ESC Working Group of Atherosclerosis and Vascular Biology. 2013. European heart journal. 34: 3251-8 A1 Journal article (refereed), original research

The impact of the receptor binding profiles of the vascular endothelial growth factors on their angiogenic features

Nieminen T, Toivanen PI, Rintanen N, Heikura T, Jauhiainen S, Airenne KJ, Alitalo K, Marjomäki V, Ylä-Herttuala S. 2013. Biochimica et biophysica acta: international journal of biochemistry and biophysics. 1840: 454-463 A1 Journal article (refereed), original research

Neuropilin-2 and vascular endothelial growth factor receptor-3 are up-regulated in human vascular malformations

Partanen TA, Vuola P, Jauhiainen S, Lohi J, Salminen P, Pitkäranta A, Häkkinen SK, Honkonen K, Alitalo K, Ylä-Herttuala S. 2012. Angiogenesis. 2012 Sep 9. [Epub ahead of print]: -- A1 Journal article (refereed), original research

Pro- and anti-angiogenic therapy and atherosclerosis with special emphasis on vascular endothelial growth factors

Vuorio, T., Jauhiainen, S., Ylä-Herttuala, S. 2012. Expert opinion on biological therapy. 2012 Jan;12(1): 79-92 A1 Journal article (refereed), original research

Regulation of endothelial lipase and systemic HDL cholesterol levels by SREBPs and VEGF-A

Kivelä AM, Dijkstra MH, Heinonen SE, Gurzeler E, Jauhiainen S, Levonen AL, Ylä-Herttuala S. 2012. Atherosclerosis. 2012 Oct 9. [Epub ahead of print]: -- A1 Journal article (refereed), original research

Vascular endothelial growth factor (VEGF)-D stimulates VEGF-A, stanniocalcin-1, and neuropilin-2 and has potent angiogenic effects

Jauhiainen Suvi, Häkkinen Sanna-Kaisa, Toivanen Pyry I, Heinonen Suvi E, Jyrkkänen Henna-Kaisa, Kansanen Emilia, Leinonen Hanna, Levonen Anna-Liisa, Ylä-Herttuala Seppo. 2011. Arteriosclerosis, thrombosis, and vascular biology. 31: 1617-1624 A1 Journal article (refereed), original research

Novel vascular endothelial growth factor D variants with increased biological activity

Toivanen PI, Nieminen T, Viitanen L, Alitalo A, Roschier M, Jauhiainen S, Markkanen JE, Laitinen OH, Airenne TT, Salminen TA, Johnson MS, Airenne KJ, Ylä-Herttuala S. 2009. Journal of biological chemistry. 284: 16037-16048 A1 Journal article (refereed), original research

Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo

Jyrkkänen H-K, Kansanen E, Inkala M, Kivelä AM, Hurttila H, Heinonen SE, Goldsteins G, Jauhiainen S, Tiainen S, Makkonen H, Oskolkova O, Afonyushkin T, Koistinaho J, Yamamoto M, Bochkov VN, Ylä-Herttuala S, Levonen A-L. 2008. Circulation research. 103: e1-e9 A1 Journal article (refereed), original research

Nrf2 gene transfer induces antioxidant enzymes and suppresses smooth muscle cell growth in vitro and reduces oxidative stress in rabbit aorta in vivo

Levonen A-L, Inkala M, Heikura T, Jauhiainen S, Jyrkkänen H-K, Kansanen E, Määttä K, Romppanen E, Turunen P, Rutanen J, Ylä-Herttuala S. 2007. Arteriosclerosis, thrombosis, and vascular biology. 27: 741-747 A1 Journal article (refereed), original research

Adenovirus-mediated gene transfer of placental growth factor to perivascular tissue induces angiogenesis via upregulation of the expression of endogenous vascular endothelial growth factor-A

Roy H, Bhardwaj S, Babu M, Jauhiainen S, Herzig K-H, Bellu AR, Haisma HJ, Carmeliet P, Alitalo K, Ylä-Herttuala S. 2005. Human gene therapy. 16: 1422-1428 A1 Journal article (refereed), original research

Gene transfer using the mature form of VEGF-D reduces neointimal thickening through nitric oxide-dependent mechanism

Rutanen J, Turunen A-M, Teittinen M, Rissanen TT, Heikura T, Koponen JK, Gruchala M, Inkala M, Jauhiainen S, Hiltunen MO, Turunen MP, Stacker SA, Achen MG, Ylä-Herttuala S. 2005. Gene therapy. 12: 980-987 A1 Journal article (refereed), original research

Periadventitial angiopoietin-1 gene transfer induces angiogenesis in rabbit carotid arteries

Bhardwaj S, Roy H, Kärpänen T, Hi Y, Jauhiainen S, Hedman M, Alitalo K, Ylä-Herttuala S. 2005. Gene therapy. 12: 388-394 A1 Journal article (refereed), original research

Fibroblast growth factor-4 induces vascular permeability, angiogenesis, and arteriogenesis in a rabbit hind limb ischemia model

Rissanen TT, Markkanen JE, Arve K, Rutanen J, Kettunen MI, Vajanto I, Jauhiainen S, Cashion L, Gruchala M, Närvänen O, Taipale P, Kauppinen RA, Rubanyi GM, Ylä-Herttuala S. 2003. Faseb journal. 17: 100-102 A1 Journal article (refereed), original research

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Proteomics on human cerebral cavernous malformations reveals novel biomarkers in neurovascular dysfunction for the disease pathology

ErbB signalling is a potential therapeutic target for vascular lesions with fibrous component

Large Vessel Cell Heterogeneity and Plasticity: Focus in Aortic Aneurysms

Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function

Beyond endothelial cells: Vascular endothelial growth factors in heart, vascular anomalies and placenta

Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain

Verisuonten seinämien somaattiset mutaatiot aivojen valtimo-laskimoepämuodostumien aiheuttajina

Differential regulation of angiogenic cellular processes and claudin-5 by histamine and VEGF via PI3K-signaling, transcription factor SNAI2 and interleukin-8

Vascular endothelial growth factors and their receptors in endothelial cells and in pathological conditions

Stabilization of atherosclerotic plaques: an update

The impact of the receptor binding profiles of the vascular endothelial growth factors on their angiogenic features

Neuropilin-2 and vascular endothelial growth factor receptor-3 are up-regulated in human vascular malformations

Pro- and anti-angiogenic therapy and atherosclerosis with special emphasis on vascular endothelial growth factors

Regulation of endothelial lipase and systemic HDL cholesterol levels by SREBPs and VEGF-A

Vascular endothelial growth factor (VEGF)-D stimulates VEGF-A, stanniocalcin-1, and neuropilin-2 and has potent angiogenic effects

Novel vascular endothelial growth factor D variants with increased biological activity

Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo

Nrf2 gene transfer induces antioxidant enzymes and suppresses smooth muscle cell growth in vitro and reduces oxidative stress in rabbit aorta in vivo

Adenovirus-mediated gene transfer of placental growth factor to perivascular tissue induces angiogenesis via upregulation of the expression of endogenous vascular endothelial growth factor-A

Gene transfer using the mature form of VEGF-D reduces neointimal thickening through nitric oxide-dependent mechanism

Periadventitial angiopoietin-1 gene transfer induces angiogenesis in rabbit carotid arteries

Fibroblast growth factor-4 induces vascular permeability, angiogenesis, and arteriogenesis in a rabbit hind limb ischemia model