Petri Mäkinen
Staff Scientist
A.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences
petri.makinen@uef.fi | +358 40 355 3683
Research groups
Publications
39/39 items-
DPYSL5 is highly expressed in treatment-induced neuroendocrine prostate cancer and promotes lineage plasticity via EZH2/PRC2
Kaarijärvi, Roosa; Kaljunen, Heidi; Nappi, Lucia; Fazli, Ladan; Kung, Sonia H. Y.; Hartikainen, Jaana M.; Paakinaho, Ville; Capra, Janne; Rilla, Kirsi; Malinen, Marjo; Mäkinen, Petri I.; Ylä-Herttuala, Seppo; Zoubeidi, Amina; Wang, Yuzhuo; Gleave, Martin E.; Hiltunen, Mikko; Ketola, Kirsi. 2024. Communications biology. 7: . 108 A1 Journal article (refereed), original research -
Insights into Prime Editing Technology: A Deep Dive into Fundamentals, Potentials and Challenges
Hosseini, Seyed Younes; Mallick, Rahul; Mäkinen, Petri; Ylä-Herttuala, Seppo. 2024. Human gene therapy. 35: 577-776 A1 Journal article (refereed), original research -
Navigating the prime editing strategy to treat cardiovascular genetic disorders in transforming heart health
Hosseini, Seyed Younes; Mallick, Rahul; Mäkinen, Petri; Ylä-Herttuala, Seppo. 2024. Expert review of cardiovascular therapy. 22: 75-89 A2 Review article, Literature review, Systematic review -
Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells
Deen, Ashik Jawahar; Adinolfi, Simone; Härkönen, Jouni; Patinen, Tommi; Liu, Xiaonan; Laitinen, Tuomo; Takabe, Piia; Kainulainen, Kirsi; Pasonen-Seppänen, Sanna; Gawriyski, Lisa M; Arasu, Uma Thanigai; Selvarajan, Ilakya; Mäkinen, Petri; Laitinen, Hanna; Kansanen, Emilia; Kaikkonen, Minna U; Poso, Antti; Varjosalo, Markku; Levonen, Anna-Liisa. 2024. Redox biology. 69: A1 Journal article (refereed), original research -
SIX2 promotes cell plasticity via Wnt/β-catenin signalling in androgen receptor independent prostate cancer
Leppänen, Noora; Kaljunen, Heidi; Takala, Eerika; Kaarijärvi, Roosa; Mäkinen, Petri I; Ylä-Herttuala, Seppo; Paatero, Ilkka; Paakinaho, Ville; Ketola, Kirsi. 2024. Nucleic acids research. 52: 5610-5623 A1 Journal article (refereed), original research -
Single-Cell Gene-Regulatory Networks of Advanced Symptomatic Atherosclerosis
Mocci, Giuseppe; Sukhavasi, Katyayani; Örd, Tiit; Bankier, Sean; Singha, Prosanta; Arasu, Uma Thanigai; Agbabiaje, Olayinka Oluwasegun; Mäkinen, Petri; Ma, Lijiang; Hodonsky, Chani J; Aherrahrou, Redouane; Muhl, Lars; Liu, Jianping; Gustafsson, Sonja; Byandelger, Byambajav; Wang, Ying; Koplev, Simon; Lendahl, Urban; Owens, Gary; Leeper, Nicholas J; Pasterkamp, Gerard; Vanlandewijck, Michael; Michoel, Tom; Ruusalepp, Arno; Hao, Ke; Ylä-Herttuala, Seppo; Väli, Marika; Järve, Heli; Mokry, Michal; C. 2024. Circulation research. 134: 1405-1423 A1 Journal article (refereed), original research -
Alzheimer's disease-induced phagocytic microglia express a specific profile of coding and non-coding RNAs
Scoyni, Flavia; Giudice, Luca; Väänänen, Mari Anna; Downes, Nicholas; Korhonen, Paula; Choo, Xin Yi; Välimäki, Nelli Noora; Mäkinen, Petri; Korvenlaita, Nea; Rozemuller, Annemieke J; de Vries, Helga E; Polo, Jose; Turunen, Tiia A; Ylä-Herttuala, Seppo; Hansen, Thomas B; Grubman, Alexandra; Kaikkonen, Minna U; Malm, Tarja. 2023. Alzheimer's & dementia. 2024; 20: 954-974 A1 Journal article (refereed), original research -
ApoA-I Nanotherapy Rescues Postischemic Vascular Maladaptation by Modulating Endothelial Cell and Macrophage Phenotypes in Type 2 Diabetic Mice
Babu, Mohan; Devi, Durga; Mäkinen, Petri; Örd, Tiit; Aavik, Einari; Kaikkonen, Minna; Ylä-Herttuala, Seppo. 2023. Arteriosclerosis, thrombosis, and vascular biology. 43: e46–e61 A1 Journal article (refereed), original research -
Intranasal administration of adenoviral vaccines expressing SARS-CoV-2 spike protein improves vaccine immunity in mouse models
Freitag, Tobias L; Fagerlund, Riku; Karam, Nihay Laham; Leppänen, Veli-Matti; Ugurlu, Hasan; Kant, Ravi; Mäkinen, Petri; Tawfek, Ahmed; Kumar, Sawan; Strandin, Tomas; Leskinen, Katarzyna; Hepojoki, Jussi; Kesti, Tapio; Kareinen, Lauri; Kuivanen, Suvi; Koivulehto, Emma; Sormunen, Aino; Laidinen, Svetlana; Khattab, Ayman; Saavalainen, Päivi; Meri, Seppo; Kipar, Anja; Sironen, Tarja; Vapalahti, Olli; Alitalo, Kari; Ylä-Herttuala, Seppo; Saksela, Kalle. 2023. Vaccine. 41: 3233-3246 A1 Journal article (refereed), original research -
Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models
Wittrahm, Rebekka; Takalo, Mari; Kuulasmaa, Teemu; Mäkinen, Petra M; Mäkinen, Petri; Končarević, Saša; Fartzdinov, Vadim; Selzer, Stefan; Kokkola, Tarja; Antikainen, Leila; Martiskainen, Henna; Kemppainen, Susanna; Marttinen, Mikael; Jeskanen, Heli; Rostalski, Hannah; Rahunen, Eija; Kivipelto, Miia; Ngandu, Tiia; Natunen, Teemu; Lambert, Jean-Charles; Tanzi, Rudolph E; Kim, Doo Yeon; Rauramaa, Tuomas; Herukka, Sanna-Kaisa; Soininen, Hilkka; Laakso, Markku; Pike, Ian; Leinonen, Ville; Haapasalo, . 2023. Neurobiology of disease. 182: A1 Journal article (refereed), original research