Tatu got his PhD in Pharmacy from University of Helsinki in 2016. He works on drug delivery to challenging target sites, for example posterior segment of the eye, tumors and central nervous system. Tatu has diverse international research background through working in Santen Pharmaceuticals in Japan as well as Kyoto University and Tokyo University of Pharmacy & Life Sciences. He holds a shared position in University of Helsinki and University of Eastern Finland. The current focus of his research is the utilization of nanoparticle drug delivery systems for targeted treatment of diseases with biomacromolecules. With the help of his international network of collaborators, the work continues to progress the field towards better medications.
Research groups
Projects
Publications
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Barcode lipids for absolute quantitation of liposomes in ocular tissues
Merivaara, Arto; Puranen, Jooseppi; Sadeghi, Amir; Zashikhina, Natalia; Pirskanen, Lea; Lajunen, Tatu; Terasaki, Tetsuya; Auriola, Seppo; Vellonen, Kati Sisko; Urtti, Arto. 2024. Journal of controlled release. 370: 1-13 A1 Journal article (refereed), original research -
Development of Focused Ultrasound-Assisted Nanoplexes for RNA Delivery
Ranjan, Sanjeev; Bosch, Stef; Lukkari, Hannamari; Schirmer, Johanna; Aaltonen, Niina; Nieminen, Heikki J; Lehto, Vesa-Pekka; Urtti, Arto; Lajunen, Tatu; Rilla, Kirsi. 2024. Nanomaterials. 14: A1 Journal article (refereed), original research -
Doxorubicin-loaded DNA origami nanostructures: stability in vitreous and their uptake and toxicity in ocular cells
Klose, Anna; Gounani, Zahra; Ijäs, Heini; Lajunen, Tatu; Linko, Veikko; Laaksonen, Timo. 2024. Nanoscale. 16: 17585-17598 A1 Journal article (refereed), original research -
PL3 CendR peptide shows specific uptake in cultured Y79 retinoblastoma cells with nucleolar accumulation
Korhonen, Sonja; Bosch, Stef; Erkinheimo, Antero; Lajunen, Tatu; Rilla, Kirsi; Teesalu, Tambet; Subrizi, Astrid; Ruponen, Marika; Urtti, Arto; Reinisalo, Mika. 2024. European journal of pharmaceutical sciences. 201: A1 Journal article (refereed), original research -
Development of Robust Cationic Light-Activated Thermosensitive Liposomes: Choosing the Right Lipids
Gangurde, Puja; Mahmoudzadeh, Mohammad; Gounani, Zahra; Koivuniemi, Artturi; Laurén, Patrick; Lajunen, Tatu; Laaksonen, Timo. 2023. Molecular pharmaceutics. 20: 5728-5738 A1 Journal article (refereed), original research -
Early-Stage Development of an Anti-Evaporative Liposomal Formulation for the Potential Treatment of Dry Eyes
Jantti, Janika; Viitaja, Tuomo; Sevon, Julia; Lajunen, Tatu; Raitanen, Jan-Erik; Schlegel, Cordula; Viljanen, Mira; Paananen, Riku O; Moilanen, Jukka; Ruponen, Marika; Ekholm, Filip. S. 2023. ACS pharmacology & translational science. 6: 1518-1530 A1 Journal article (refereed), original research -
Establishing a simple perfusion cell culture system for light-activated liposomes
Mäki-Mikola, Eija; Lauren, Patrick; Uema, Natsumi; Kikuchi, Kanako; Takashima, Yuuki; Laaksonen, Timo; Lajunen, Tatu. 2023. Scientific reports. 13: . 2050 A1 Journal article (refereed), original research -
Selective drug delivery to the retinal cells: Biological barriers and avenues
Ramsay, Eva; Lajunen, Tatu; Bhattacharya, Madhushree; Reinisalo, Mika; Rilla, Kirsi; Kidron, Heidi; Terasaki, Tetsuya; Urtti, Arto. 2023. Journal of controlled release. 361: 1-19 A1 Journal article (refereed), original research -
Imaging, quantitation and kinetic modelling of intravitreal nanomaterials
Sadeghi, Amir; Ruponen, Marika; Puranen, Jooseppi; Cao, Shoupeng; Ridolfo, Roxane; Tavakoli, Shirin; Toropainen, Elisa; Lajunen, Tatu; Ranta, Veli-Pekka; van Hest, Jan; Urtti, Arto. 2022. International journal of pharmaceutics. 621: A1 Journal article (refereed), original research -
Liposomal sunitinib for ocular drug delivery: A potential treatment for choroidal neovascularization
Tavakoli, Shirin; Puranen, Jooseppi; Bahrpeyma, Sina; Lautala, Veera E.; Karumo, Suvi; Lajunen, Tatu; del Amo, Eva M.; Ruponen, Marika; Urtti, Arto. 2022. International journal of pharmaceutics. 620: A1 Journal article (refereed), original research