Prasanthi Medarametla
Yliopistotutkija
Farmasian laitos, Terveystieteiden tiedekunta
Antibacterial drug discovery
Julkaisut
8/8 kappaletta-
Pseudomonas aeruginosa acyl-CoA dehydrogenases and structure-guided inversion of their substrate specificity
Wang, Meng; Medarametla, Prasanthi; Kronenberger, Thales; Deingruber, Tomas; Brear, Paul; Figueroa, Wendy; Ho, Pok-Man; Krueger, Thomas; Pearce, James C.; Poso, Antti; Wakefield, James G.; Spring, David R.; Welch, Martin. 2025. Nature communications. 16: . 2334 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
Structural Characterization of LsrK as a Quorum Sensing Target and a Comparison between X-ray and Homology Models
Medarametla, Prasanthi; Kronenberger, Thales; Laitinen, Tuomo; Poso, Antti. 2021. Journal of chemical information and modeling -
Identification and Design of New Antibacterial Agents Using Computational Approaches
Medarametla, Prasanthi. 2020. Publications of the University of Eastern Finland. Dissertations in Health Sciences -
DPD-Inspired Discovery of Novel LsrK Kinase Inhibitors: An Opportunity To Fight Antimicrobial Resistance
Stotani, Silvia; Gatta, Viviana; Medarametla, Prasanthi; Padmanaban, Mohan; Karawajczyk, Anna; Giordanetto, Fabrizio; Tammela, Päivi; Laitinen, Tuomo; Poso, Antti; Tzalis, Dimitros; Collina, Simona. 2019. Journal of medicinal chemistry -
Molecular Modelling Approaches to Antibacterial Drug Design and Discovery
Kaczor, Agnieszka A; Medarametla, Prasanthi; Bartuzi, Damian; Kondej, Magdalena; Matosiuk, Dariusz; Poso, Antti. 2018. Frontiers in Anti-Infective Drug Discovery -
Structure-based virtual screening of LsrK kinase inhibitors to target quorum sensing
Medarametla, Prasanthi; Gatta, Viviana; Kajander, Tommi; Laitinen, Tuomo; Tammela, Päivi; Poso Antti. 2018. Chemmedchem -
A QSAR and molecular modelling study towards new lead finding: polypharmacological approach to Mycobacterium tuberculosis
Janardhan S, John L, Prasanthi M, Poroikov V, Narahari Sastry G. 2017. Sar and qsar in environmental research -
Structural and Functional Characterization of Malate Synthase G from Opportunistic Pathogen Pseudomonas aeruginosa
McVey Alyssa C, Medarametla Prasanthi, Chee Xavier, Bartlett Sean, Poso Antti, Spring David R, Rahman Taufiq, Welch Martin. 2017. Biochemistry