Prasanthi  Medarametla

Prasanthi Medarametla

Senior Researcher

Antibacterial drug discovery by targeting virulence and pathogenicity

School of Pharmacy, Faculty of Health Sciences

Bacterial resistance is one of the rising problems that needs to be addressed. To combat the antibiotic resistance of bacteria it is necessary to identify novel antibacterial agents by targeting novel pathways such as virulence and pathogenicity.

My main interest is to validate novel targets involved in bacterial virulence, metabolism, and growth using computational approaches. Additionally we are interested in fundamental biology of bacterial metabolism and virulence during infections. Our current focus is on Pseudomonas aeruginosa, an opportunistic pathogen.

We are happy to collaborate with other groups to utilise molecular modelling approaches such as docking, virtual screening, QSAR model development, Machine learning models, and Molecular Dynamics (MD) to understand the protein-small molecule interactions and binding mechanisms.

If you are interested for any Master’s projects or would like to pursue Doctoral studies in the field of antibacterial targets (proteins) or Molecular Modelling, please feel free to write to me.



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