Prasanthi Medarametla

Bacterial resistance is one of the rising problems that needs to be addressed. To combat the antibiotic resistance of bacteria it is necessary to identify novel antibacterial agents by targeting novel pathways such as virulence and pathogenicity.

My research focuses on validating novel targets involved in bacterial virulence, metabolism, and growth using computational approaches. We are also interested in the fundamental biology of bacterial metabolism and virulence during infections, with a current emphasis on Pseudomonas aeruginosa, an opportunistic pathogen of clinical importance.

We are happy to collaborate with other groups to utilise molecular modelling approaches such as docking, virtual screening, QSAR model development, Machine learning models, and Molecular Dynamics (MD) to understand the protein-small molecule interactions and binding mechanisms.

If you’re interested in Master’s projects or planning to pursue a PhD related to antibacterial protein targets and the mechanisms underlying bacterial virulence, feel free to reach out—I’d be happy to discuss potential opportunities.