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Cardiovascular imaging and predictive markers

Research group
01.01.2022 -
Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences
Faculty of Health Sciences

Leaders

PROJECTS

DilAo Project Research investigating factors that predict aortic dilation and rupture

SUB‑PROJECTS

DilAo‑Pre – Experimental study investigating the pathophysiology of aortic dilation and imaging parameters predicting rupture (UEF; A. I. Virtanen Institute)

DilAo‑TAV – Study using modern 4D flow MRI to identify predictors of aortic dilation in patients with a normal tricuspid aortic valve (KYS)

DilAo‑BAV – Study using modern 4D flow MRI to identify predictors of aortic dilation in patients with a congenital bicuspid aortic valve + aortic coarctation (KYS, K‑SKS)

DilAo‑Ela – Study assessing aortic rupture susceptibility using biomechanical methods and histopathology (KYS, UEF; Department of Applied Physics and A. I. Virtanen Institute)

DilAo‑Sim – Study assessing aortic rupture susceptibility through mathematical modeling and pressure‑condition simulations (KYS, JAMK)

DiReA‑Digitwin – Digital and real‑elastic twin for predicting aortic dilation and rupture risk

Cardio‑Fib Project – Cardiac muscle fibrosis imaging – Development of modern radiation‑free and contrast‑free imaging methods and analysis of computational fibrosis in relation to cardiac disease prognosis and treatment outcomes

Translational cardiac perfusion imaging using different imaging techniques

Cooperation

  • Karolinska Institut

Teams and collaborators

  • PO BOX 100, 70029 KYS, Finland

    Heart Center, Heart and lung surgery

    • Marja Hedman, MD, professor, leader of the study
    • Annastiina Husso, MD, PhD, heart surgeon
    • Antti Valtola, MD, adj. professor, heart surgeon
    • Juhana Toimela, MD, PhD researcher
    • Tarmo Korpela, BMSc, PhD researcher
    • Iida Viitala, MD, PhD researcher
    • Lari Kujanen, BSc, study coordinator

     

    Clinical Imaging Center

    Clinical Radiology and Clinical Physiology and Nuclear Imaging
    • Petteri Kauhanen, MD, PhD, post doc researcher
    • Saara Sillanmäki, MD, PhD, post doc researcher
    • Line Lottonen-Raikaslehto, MD, PhD, post doc researcher
    • Minna Husso, MSc, PhD, hospital physicist
    • Elias Ylä-Herttuala, MSc, PhD, hospital physicist
    • Petri Saari, MD, PhD, vascular radiologist
    • Hanna Matikka, MSc, PhD, hospital physicist
    • Sami Väänänen, MSc, Phd, hospital physicist

     

    Department of Anestesiology and Intensive care

    • Petri Toroi, BSc, study nurse
    • Maarit Lång, MD, PhD, clinical collaborator
  • PO BOX 1627, 70211 Kuopio, Finland

    A.I.Virtanen Institute Molecular Sciences

    • Johanna Laakkonen, PhD, associate professor
    • Miika Kiema, MSc, doctoral researcher
    • Heta Rasinkangas, medical student, doctoral researcher
    • Akseli Kivistö-Rahnasto, medical student, researcher
    • Emma-Sofia Luoto, medical student, researcher
    • Suvi Jauhiainen, PhD, project researcher
    • Jussi Tohka, PhD, professor of biomedical image analysis

     

    Department of Applied Physics

    • Jaakko Sarin, PhD, docent
    • Jari Torniainen, PhD, post doc researcher
  • PO BOX 207, 40101 Jyväskylä, Finland

    Industrial engineering

    • Matti Kurki, adjunct professor, principal researcher
    • Tero Tuovinen, adjunct professor, researcher
    • Tomi Nieminen, lector, researcher
  • 17177 Stockholm, Sweden

    Dept. of Molecular Medicine and Surgery

    • David Marlevi, MD, PhD, post doc researcher
    • Martin Ugander, MD, professor
    • Klara Blomdahl, MD, PhD researcher
    • Martin Ugander, MD, professor
  • Mulhouse, France

    • Frederic Heim, MS, professor

Keywords