
Leaders
Group description
Our group studies the molecular mechanisms of neurodegeneration involved in the pathogenesis of frontotemporal dementia (FTD). FTD is the most common cause of dementia in under 60-year-olds. We especially focus on the genetic form of FTD caused by the hexanucleotide repeat expansion in the C9orf72 gene, because it is exceptionally common in Finnish FTD patients. We are interested in molecular pathogenetic and functional changes in neurons and microglia derived from FTD patients. We also aim to identify novel biomarkers to help differential diagnostics of different forms of FTD. We are active participants of the Finnish FTD Research Network, FinFTD, and we closely collaborate with FTD clinical researchers with the goal of translating our findings for the benefit of the patients. We are also part of the EU JPND and Academy of Finland -funded SynaDeg project (Pre-diagnostic early synaptic disturbances in neurodegenerative diseases), where we act as a partner and coordinator.
Follow us in X: @HaapasaloLab.
News
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We are a partner and coordinator of the JPND SynaDeg project
Projects
Cooperation
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Finnish FTD Research Network (FinFTD) 01.05.2016 -
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AIVI Stem Cell Center
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Bioinformatics Center 01.01.2014 -
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Biomarkers for Neurological Disorders 08.06.2004 -
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Frontotemporal Lobar Degeneration and Early Onset Dementia 01.01.2022 -
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GenomMed Finished 01.04.2018 - 31.12.2022
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Molecular Genetics of Alzheimer's Disease 01.01.2022 -
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Neuroinflammation research group 01.01.2017 -
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Neurobiology of Memory 12.11.2022 -
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UEF Neurodegeneration - Myohanen Lab 02.08.2021 -
Keywords
Leaders
Professors
Post-doctoral Researchers
Doctoral Researchers
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Nadine Huber
Grant-funded ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences -
Tomi Hietanen
Grant-funded ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences -
Elena Ppali
Early Stage ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences
Previous group members
Other group members
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Viivi Pekkala